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泰国肺吸虫病与肺结核的合并感染

Coinfection of Pulmonary Paragonimiasis and Pulmonary Tuberculosis in Thailand.

作者信息

Petborom Pichaya, Linasmita Patcharasarn, Kulpraneet Manaphol

出版信息

J Med Assoc Thai. 2016 Nov;99 Suppl 8:S231-S236.

Abstract

The authors report a case of coinfection of pulmonary paragonimiasis and pulmonary tuberculosis which is an uncommon coinfection. The patient presented with a one-week history of nonmassive hemoptysis about 1 month after completion of treatment for smear-negative pulmonary tuberculosis (sputum polymerase chain reaction positive for Mycobacterium tuberculosis). She lived in Nakhon Nayok province and reported taking raw crabs from time to time. The complete blood count revealed eosinophilia and her chest radiograph showed patchy infiltration at right lower lung field. Computed tomography scan of the chest revealed consolidation with internal air bubbles at anterobasal segment of right lower lobe. The diagnosis of pulmonary paragonimiasis was confirmed by detecting eggs of the genus Paragonimus in her wet-mount sputum. She was treated with oral praziquantel for 3 consecutive days with improvement. To our knowledge, although coinfection of pulmonary paragonimiasis and pulmonary tuberculosis is rare, it should be considered as the differential diagnosis in patients who live in the endemic area presenting with hemoptysis and eosinophilia.

摘要

作者报告了一例肺吸虫病与肺结核合并感染的病例,这种合并感染并不常见。该患者在涂片阴性的肺结核治疗结束约1个月后,出现了为期一周的少量咯血病史(痰结核分枝杆菌聚合酶链反应阳性)。她居住在那空那育府,报告称不时食用生蟹。全血细胞计数显示嗜酸性粒细胞增多,胸部X光片显示右下肺野有斑片状浸润。胸部计算机断层扫描显示右下叶前基底段实变并伴有内部气泡。通过在其湿涂片痰中检测到肺吸虫属虫卵,确诊为肺吸虫病。她连续3天接受口服吡喹酮治疗,病情有所改善。据我们所知,尽管肺吸虫病与肺结核的合并感染很少见,但对于生活在流行地区出现咯血和嗜酸性粒细胞增多的患者,应将其视为鉴别诊断之一。

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