Pellicano Mariano, Floré Vincent, Barbato Emanuele, De Bruyne Bernard
Cardiovascular Center Aalst, OLV Hospital, Moorselbaan 164, B 9300, Aalst, Belgium.
Department of Advanced Biomedical Sciences, Federico II University of Naples, Via Pansini, 5, 80131, Naples, Italy.
BMC Cardiovasc Disord. 2018 Jun 19;18(1):122. doi: 10.1186/s12872-018-0860-y.
Percutaneous coronary interventions (PCI) of old calcified saphenous vein grafts (SVGs) is challenging and is associated with a considerably high risk of adverse ischemic events in the short- and long-term as compared to native coronary arteries. We report a case in which a non-dilatable, calcified SVG lesion is successfully treated with rotational atherectomy followed by PCI and stenting with local stent delivery (LSD) technique using the Guidezilla™ guide extension catheter (5-in-6 Fr) in the "child-in-mother" fashion.
A 70 years-old man with a dilated ischemic cardiomyopathy, triple coronary artery bypass grafting (CABG) in 1990 and chronic renal failure (baseline GFR: 45 ml/min/1.73 m) underwent a coronary angiography for a Non-ST segment elevation myocardial infarction (NSTEMI). Native coronary circulation was completely occluded at the proximal segments. Grafts angiography showed a tandem calcified lesions of SVG on distal right coronary artery (RCA) and an ostial stenosis of the SVG on first obtuse marginal branch (OM1). Left internal mammary artery on the mid left anterior descending artery was patent. Ad Hoc PCI of SVG on RCA was attempted. The proximal calcified stenosis has been crossed with a 1.5 x 12 mm balloon only with the support of Guidezilla™, however the non-compliant (NC) balloon 2.5 x 15 mm was unable to break the hard and calcified plaque. After several attempts, the procedure was interrupted with a suboptimal result. An elective transradial PCI of SVG on RCA with rotational atherectomy was performed. Two runs with 1.25 mm burr and 2 runs with 1.5 mm burr were carried out. Then, the use of distal anchoring balloon warranted support and tracking, made as centring rail for the advance of the tip of the "mother-and-child" catheter into the SVG. During slow deflation of the balloon, the Guidezilla™ was advanced distal to the stenoses to be stented, thus allowing the placement of two long drug eluting stents according to a LSD technique.
Rotational atherectomy is a feasible option for non-dilatable stenoses in old SVGs when there is no evidence of thrombus or vessel dissection and the subsequent use of "mother-and-child" catheter has a key role, especially in case of radial approach, for long stents delivery.
与天然冠状动脉相比,对陈旧性钙化大隐静脉桥血管(SVG)进行经皮冠状动脉介入治疗(PCI)具有挑战性,且在短期和长期内均伴有相当高的不良缺血事件风险。我们报告了一例病例,其中一个不可扩张的钙化SVG病变通过旋磨术成功治疗,随后采用“子母”方式使用Guidezilla™ 引导延长导管(5-in-6 Fr)进行PCI及局部支架置入术(LSD)。
一名70岁男性,患有扩张型缺血性心肌病,于1990年接受了冠状动脉搭桥术(CABG),并患有慢性肾衰竭(基线肾小球滤过率:45 ml/min/1.73 m²),因非ST段抬高型心肌梗死(NSTEMI)接受冠状动脉造影。天然冠状动脉近端节段完全闭塞。桥血管造影显示右冠状动脉(RCA)远端SVG存在串联钙化病变,第一钝缘支(OM1)上SVG存在开口处狭窄。左前降支中段的左内乳动脉通畅。尝试对RCA上的SVG进行临时PCI。仅在Guidezilla™ 的支撑下,用一个1.5×12 mm的球囊穿过了近端钙化狭窄,但2.5×15 mm的非顺应性(NC)球囊无法破开坚硬的钙化斑块。经过多次尝试后,手术因效果不理想而中断。对RCA上的SVG进行了择期经桡动脉PCI并联合旋磨术。使用1.25 mm的磨头进行了两次旋磨,使用1.5 mm的磨头进行了两次旋磨。然后,使用远端锚定球囊保证支撑和跟踪,将其作为“子母”导管尖端进入SVG的中心轨道。在球囊缓慢放气过程中,将Guidezilla™ 推进到要置入支架的狭窄远端,从而能够根据LSD技术置入两枚长药物洗脱支架。
当没有血栓或血管夹层证据时,旋磨术是治疗陈旧SVG中不可扩张狭窄的可行选择,随后使用“子母”导管具有关键作用,尤其是在经桡动脉途径的情况下,对于长支架置入。