Department of Medicine, Division of Cardiology, University of Washington, Seattle, Washington, USA.
Heart. 2018 Nov;104(21):1771-1802. doi: 10.1136/heartjnl-2018-312966. Epub 2018 Jun 22.
A man in his early 30s with remote history of a febrile rash as a toddler presented to the emergency room following an out-of-hospital cardiac arrest while riding his bicycle. He received bystander cardiopulmonary resuscitation and one shock from an automatic external defibrillator, successfully restoring sinus rhythm. On arrival, he was haemodynamically stable without ECG evidence of ST segment changes to suggest active ischaemia, and an initial troponin I was mildly elevated at 0.10 ng/mL (normal <0.04 ng/mL). A CT angiogram (CTA) was obtained showing a normal-appearing aorta and no abnormal extracardiac findings. Urgent coronary angiography was performed; images are shown in figure 1A-C. Echocardiogram revealed a mildly reduced left ventricular ejection fraction (45%) with a hypokinetic inferior wall.heartjnl;104/21/1771/F1F1F1Figure 1(A) Right coronary artery angiogram in the left anterior oblique cranial projection. (B) Left coronary artery angiogram in the right anterior oblique caudal projection. (C) Left coronary artery angiogram in the right anterior oblique cranial projection. CAUD, caudal; CRAN, cranial; LAO, left anterior oblique; RAO, right anterior oblique.
What is the next best step in the management of this patient at this time?Complete revascularisation via percutaneous coronary intervention (PCI).Referral for coronary artery bypass surgery (CABG).Initiation of high-dose steroids.Initiation of dual-antiplatelet therapy without planned revascularisation.
一名 30 岁出头的男性,幼儿时有发热性皮疹史,在骑自行车时发生院外心脏骤停,随后被送往急诊室。他接受了旁观者心肺复苏和一次自动体外除颤器电击,成功恢复窦性心律。到达时,他血流动力学稳定,心电图无 ST 段变化提示有活动性缺血,初始肌钙蛋白 I 轻度升高至 0.10ng/mL(正常值<0.04ng/mL)。进行了 CT 血管造影(CTA),显示主动脉正常,无异常心脏外发现。紧急进行冠状动脉造影;图像如图 1A-C 所示。超声心动图显示左心室射血分数轻度降低(45%),下壁运动减弱。heartjnl;104/21/1771/F1F1F1图 1(A)左前斜颅位右冠状动脉造影。(B)右前斜尾位左冠状动脉造影。(C)右前斜颅位左冠状动脉造影。CAUD,尾侧;CRAN,头侧;LAO,左前斜位;RAO,右前斜位。
此时患者下一步最佳治疗方法是什么?经皮冠状动脉介入治疗(PCI)进行完全血运重建。转诊行冠状动脉旁路移植术(CABG)。开始大剂量类固醇治疗。开始双联抗血小板治疗而不计划血运重建。