晚期胃癌伴腹膜转移的治疗策略演变与疗效
Evolving Treatment Strategies and Outcomes in Advanced Gastric Cancer with Peritoneal Metastasis.
作者信息
Dahdaleh Fadi S, Turaga Kiran K
机构信息
Complex General Surgical Oncology, Section of General Surgery/Surgical Oncology, The University of Chicago Medicine, 5841 South Maryland Avenue, Room S214, MC 5094, Chicago, IL 60637, USA.
The University of Chicago Medicine, Section of General Surgery/Surgical Oncology, 5841 South Maryland Avenue, Room G207, MC 5094, Chicago, IL 60637, USA.
出版信息
Surg Oncol Clin N Am. 2018 Jul;27(3):519-537. doi: 10.1016/j.soc.2018.02.006.
Gastric cancer (GC) has a predilection to metastasize to the peritoneum, denoting a poor prognosis. Treatment strategies available for advanced GC have significantly evolved over time and can be categorized into systemic, regional, and surgical. Although systemic therapies have been the mainstay for the treatment of advanced GC, their ability in achieving long-term survival in patients with peritoneal involvement is modest at best. This article describes advances in combined modality treatment of peritoneal metastases, specifically with an emphasis on peritoneal-directed therapies.
胃癌（GC）易于转移至腹膜，这意味着预后较差。随着时间的推移，晚期GC可用的治疗策略有了显著进展，可分为全身治疗、区域治疗和手术治疗。尽管全身治疗一直是晚期GC治疗的主要手段，但其使腹膜受累患者实现长期生存的能力充其量也很有限。本文描述了腹膜转移联合治疗模式的进展，尤其着重于针对腹膜的治疗方法。
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