Masucci Lisa, Erman Aysegul, Krahn Murray D, Elterman Dean
Toronto Health Economics and Technology Assessment Collaborative (THETA), University of Toronto.
Institute of Health Policy, Management, and Evaluation.
Can Urol Assoc J. 2018 Dec;12(12):382-387. doi: 10.5489/cuaj.5267.
Benign prostatic hyperplasia (BPH) is a non-cancerous enlargement of the prostate gland, which results in the development of lower urinary tract symptoms that can interfere with a patient's daily activities and negatively impact their quality of life. The gold standard treatment for moderate to severe BPH has been transurethral resection of the prostate (TURP), however, this procedure is associated with prolonged hospitalizations and increased complications. An alternative to TURP is Greenlight photoselective vaporization of the prostate (PVP), which is associated with better perioperative safety. The objectives of the research were to 1) assess the cost of Greenlight PVP compared to TURP and bipolar TURP; and 2) assess the predictors of total cost.
We conducted a descriptive costing study from the hospital perspective. We evaluated perioperative costs of patients who underwent each procedure from 2013-2015 at a tertiary academic medical centre. A multiple linear regression was performed to identify predictors of total cost. The variables included in regression analysis were patient age, type of procedure, Charlson Comorbidity Index, and distance to clinic.
A total of 202 patients received one of the three procedures over the study period. The total cost of Greenlight PVP was $3836 per patient compared to $4963 for TURP and $4978 for bipolar TURP. The linear regression showed that the Charlson Comorbidity Index and type of procedure were independent predictors of total cost.
The procedure costs and readmission rates are lower for Greenlight PVP compared to TURP and bipolar TURP, making it a preferable option for hospitals.
良性前列腺增生(BPH)是前列腺的非癌性肿大,会导致下尿路症状的出现,这些症状会干扰患者的日常活动并对其生活质量产生负面影响。中重度BPH的金标准治疗方法一直是经尿道前列腺切除术(TURP),然而,该手术与住院时间延长和并发症增加有关。TURP的一种替代方法是绿激光前列腺选择性汽化术(PVP),其围手术期安全性更好。本研究的目的是:1)评估绿激光PVP与TURP和双极TURP相比的成本;2)评估总成本的预测因素。
我们从医院角度进行了一项描述性成本研究。我们评估了2013年至2015年在一家三级学术医疗中心接受每种手术的患者的围手术期成本。进行了多元线性回归以确定总成本的预测因素。回归分析中纳入的变量包括患者年龄、手术类型、查尔森合并症指数和到诊所的距离。
在研究期间,共有202名患者接受了三种手术中的一种。绿激光PVP的每位患者总成本为3836美元,而TURP为4963美元,双极TURP为4978美元。线性回归表明,查尔森合并症指数和手术类型是总成本的独立预测因素。
与TURP和双极TURP相比,绿激光PVP的手术成本和再入院率更低,使其成为医院更优的选择。