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急性慢性阻塞性肺疾病加重期伴明显肺大疱内出血和咯血。

Acute COPD exacerbation presenting with pronounced intrabullous haemorrhage and haemoptysis.

作者信息

Runggaldier Daniel, Minami Taro, Golding Daniel, Manzoor Kamran

机构信息

Department of Otorhinolaryngology, University Hospital of Zurich, Zurich, Switzerland.

Division of Pulmonary, Critical Care and Sleep Medicine, Memorial Hospital of Rhode Island, Providence, Rhode Island, USA.

出版信息

BMJ Case Rep. 2018 Jun 28;2018:bcr-2018-225339. doi: 10.1136/bcr-2018-225339.

Abstract

A 54-year-old man with history of chronic obstructive pulmonary disease (COPD) presented with subacute onset of chest pain, shortness of breath, productive cough with haemoptysis and night sweats. There were no fever or recent weight loss reported. The chest radiograph showed right upper lobe bullae with adjacent opacification and an emphysematous lung. Due to worsening haemoptysis and persistent chest pain, CT of the chest with contrast was performed, which revealed moderate to severe emphysema and numerous blood-filled bullae. Cardiac work-up for chest pain was negative for myocardial ischaemia and for aortic dissection. Further infectious work-ups for mycobacterial and invasive fungal infection were negative. The patient was treated for acute COPD exacerbation and responded well to the antibiotics with the resolution of haemoptysis. Follow-up CT of the chest revealed the gradual resolution of the haemorrhage, while the patient remained asymptomatic.

摘要

一名54岁有慢性阻塞性肺疾病(COPD)病史的男性,出现亚急性胸痛、气短、咳血痰伴盗汗。未报告发热或近期体重减轻情况。胸部X光片显示右上叶肺大疱伴相邻肺实变及肺气肿。由于咯血加重和持续胸痛,进行了胸部增强CT检查,结果显示中度至重度肺气肿及大量充满血液的肺大疱。针对胸痛进行的心脏检查未发现心肌缺血和主动脉夹层。针对分枝杆菌和侵袭性真菌感染的进一步感染性检查结果为阴性。该患者接受了急性COPD加重期的治疗,对抗生素反应良好,咯血症状得以缓解。胸部随访CT显示出血逐渐吸收,患者仍无症状。

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本文引用的文献

1
Chronic obstructive pulmonary disease.慢性阻塞性肺疾病。
Nat Rev Dis Primers. 2015 Dec 3;1:15076. doi: 10.1038/nrdp.2015.76.
6
Acute hemorrhage in a giant bulla.巨大肺大疱内的急性出血。
Intern Med. 2012;51(18):2673. doi: 10.2169/internalmedicine.51.8335. Epub 2012 Sep 15.

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