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灵长类动物视觉长期记忆检索的脑机制

Brain mechanisms of visual long-term memory retrieval in primates.

作者信息

Takeda Masaki

机构信息

Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan; Department of Physiology, The University of Tokyo School of Medicine, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan; Research Center for Brain Communication, Research Institute, Kochi University of Technology, Kami-city, Kochi 782-8502, Japan.

出版信息

Neurosci Res. 2019 May;142:7-15. doi: 10.1016/j.neures.2018.06.005. Epub 2018 Jun 30.

Abstract

Memorizing events or objects and retrieving them from memory are essential for daily life. Historically, memory processing was studied in neuropsychology, in which patients provided us with insights into the brain mechanisms underlying memory. Psychological hypotheses about memory processing have been further investigated using neuroscience techniques, such as functional imaging and electrophysiology. In this article, I briefly summarize recent findings on multi-scale neural circuitry for memory at the scale of single neurons and cortical layers as well as inter-area and whole-brain interactions. The key idea which connects multi-scale neural circuits is how neuronal assemblies utilize the frequency of communication between neurons, cortical layers, and brain areas. Using findings and ideas from other cognitive function studies, I discuss the plausible communication between neurons involved in memory.

摘要

记忆事件或物体并从记忆中检索它们对日常生活至关重要。从历史上看,记忆处理是在神经心理学中进行研究的,在神经心理学中,患者为我们提供了对记忆背后大脑机制的见解。关于记忆处理的心理学假设已通过神经科学技术(如功能成像和电生理学)得到进一步研究。在本文中,我简要总结了关于记忆的多尺度神经回路的最新发现,这些发现涉及单个神经元和皮层层的尺度,以及区域间和全脑的相互作用。连接多尺度神经回路的关键思想是神经元集群如何利用神经元、皮层层和脑区之间的通信频率。利用其他认知功能研究的发现和观点,我讨论了参与记忆的神经元之间可能的通信。

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