Department of Parasitology, Vietnam Military Medical University (VMMU), Phung Hung Street, Ha Dong Town, Hanoi, Vietnam.
Department of Dermatological Disease, Hospital 103, Vietnam Military Medical University (VMMU), Hanoi, Vietnam.
Mycopathologia. 2019 Feb;184(1):115-119. doi: 10.1007/s11046-018-0284-3. Epub 2018 Jul 4.
Chromoblastomycosis is a chronic fungal infection of the skin and subcutaneous tissues caused by different melanized fungi. The disease occurs worldwide, particularly in tropical and subtropical regions but not reported in Vietnam. A 47-year-old women was admitted to hospital 103, Hanoi, Vietnam, with a 10-year lasting lesion on backside of her right shank. Diagnosis of chromoblastomycosis was made after discovery of a muriform cell in histopathological examination. A black, slow-growth fungus was isolated and identified as Fonsecaea pedrosoi after molecular analysis. After 1-month treatment with itraconazole, the lesion has significant improvement.
This is the first case of chromoblastomycosis caused by Fonsecaea pedrosoi reported in Vietnam.
着色芽生菌病是一种由不同的黑素真菌引起的皮肤和皮下组织的慢性真菌感染。该病分布于世界各地，特别是在热带和亚热带地区，但越南尚未有报道。一名 47 岁女性因右小腿后侧存在 10 年的皮损入住越南河内的 103 医院。在组织病理学检查中发现多形态细胞后，诊断为着色芽生菌病。经分子分析后，从患者皮损中分离出一种黑色、生长缓慢的真菌，鉴定为佩氏着色霉。伊曲康唑治疗 1 个月后，皮损明显改善。
这是越南首例由佩氏着色霉引起的着色芽生菌病。
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