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[多支冠状动脉疾病合并难治性心源性休克患者行复杂经皮冠状动脉血运重建时的高危ST段抬高型急性冠状动脉综合征:机械循环支持装置的作用及时机]

[High-risk ST-elevation acute coronary syndrome in a patient with multivessel coronary artery disease complicated by refractory cardiogenic shock undergoing complex percutaneous coronary revascularization: role and timing of mechanical circulatory support devices].

作者信息

Masiero Giulia, Pavei Andrea, Fraccaro Chiara, Napodano Massimo, Tarantini Giuseppe

机构信息

Dipartimento di Scienze Cardiache, Toraciche e Vascolari, Policlinico Universitario, Padova.

出版信息

G Ital Cardiol (Rome). 2018 Jun;19(6 Suppl 1):36S-41S. doi: 10.1714/2939.29548.

Abstract

Cardiogenic shock (CS) following acute myocardial infarction complicated by severe ventricular dysfunction remains the leading cause of death despite customized pharmacological therapy and optimal revascularization. The use of temporary mechanical circulatory support (MCS) devices during refractory CS might represent the only chance of survival to address the underlying systemic inflammatory response preventing the development of multiorgan failure. We report the case of a patient with a very-high-risk non-ST-elevation acute coronary syndrome and multivessel calcific coronary artery disease complicated by refractory CS undergoing complex percutaneous coronary revascularization. We show a gradual and complementary use of MCS devices tailored on hemodynamic monitoring, clinical and laboratory variables and multidisciplinary collaboration to early recognize the downward spiral that may ensue with multiorgan dysfunction or potential complications leading to death.

摘要

尽管有定制的药物治疗和最佳的血运重建,但急性心肌梗死后并发严重心室功能障碍的心源性休克(CS)仍然是主要的死亡原因。在难治性CS期间使用临时机械循环支持(MCS)设备可能是解决潜在的全身炎症反应、防止多器官功能衰竭发展的唯一生存机会。我们报告了一例患有极高风险非ST段抬高急性冠状动脉综合征和多支钙化冠状动脉疾病并并发难治性CS的患者,该患者接受了复杂的经皮冠状动脉血运重建。我们展示了根据血流动力学监测、临床和实验室变量以及多学科协作量身定制的MCS设备的逐步和互补使用,以便早期识别可能因多器官功能障碍或潜在并发症导致死亡而出现的恶性循环。

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