Sirimaharaj Wimon, Charoenvicha Chirakan
1 Chiang Mai University, Chiang Mai, Thailand.
Int J Low Extrem Wounds. 2018 Jun;17(2):94-101. doi: 10.1177/1534734618779858.
The aim of this study was to identify overall recurrence rates after reconstructive surgery in patients with pressure ulcers and to identify risk factors that associated with recurrence after reconstructive surgery. This study was done in Faculty of Medicine Chiang Mai University, including recurrence at the same site as well as on new sites, between January 1998 and December 2015. 165 patients with 272 pressure ulcers were retrospectively collected and analyzed. The overall pressure ulcer recurrence rate was 16.54% (45 from 272 ulcers) from an overall patient recurrence of 19.39% (32 from 165 patients). From multivariable analysis, we found 9 prognostic factors that were statistically significant for recurrence after surgery, divided into 2 groups: uncontrollable and controllable factors. Uncontrollable factors consisted of being female (hazard ratio [HR]=1.90;95%CI=1.54-2.34), being older than 45 years (HR=1.67;95%CI=1.40-2.0), and location of pressure ulcers on ischium (HR=1.65; 95% CI=1.51-1.80) and sacrum (HR=1.17;95%CI=1.10-1.23). Controllable factors included spasticity (HR=1.11;95%CI=1.04-1.20), incomplete healing before discharge (HR=5.42;95% CI=3.95-7.44), serum albumin level ≤3 g/dL (HR=1.27;95%CI=1.13-1.43), pressure ulcer stage 4 (HR=1.90;95%CI=1.41-2.54), non -muscle-based procedure (HR=3.82;95%CI=2.54-5.76), and length of hospitalization >21 days (HR=2.94;95%CI=1.60-5.40). Patients with these factors were strongly advised to address and improve all these factors for decreasing the recurrence rate after reconstructive surgery.
本研究的目的是确定压疮患者重建手术后的总体复发率,并确定与重建手术后复发相关的危险因素。本研究在清迈大学医学院进行,研究时间为1998年1月至2015年12月,包括同一部位以及新部位的复发情况。回顾性收集并分析了165例患者的272处压疮。压疮总体复发率为16.54%(272处溃疡中有45处复发),患者总体复发率为19.39%(165例患者中有32例复发)。通过多变量分析,我们发现9个对术后复发具有统计学意义的预后因素,分为两组:不可控因素和可控因素。不可控因素包括女性(风险比[HR]=1.90;95%置信区间[CI]=1.54 - 2.34)、年龄大于45岁(HR=1.67;95%CI=1.40 - 2.0)、压疮位于坐骨(HR=1.65;95%CI=1.51 - 1.80)和骶骨(HR=1.17;95%CI=1.10 - 1.23)。可控因素包括痉挛(HR=1.11;95%CI=1.04 - 1.20)、出院前未完全愈合(HR=5.42;95%CI=3.95 - 7.44)、血清白蛋白水平≤3g/dL(HR=1.27;95%CI=1.13 - 1.43)、4期压疮(HR=1.90;95%CI=1.41 - 2.54)、非肌肉皮瓣手术(HR=3.82;95%CI=2.54 - 5.76)以及住院时间>21天(HR=2.94;95%CI=1.60 - 5.40)。强烈建议存在这些因素的患者处理并改善所有这些因素,以降低重建手术后的复发率。