抗生素对肠道微生物组的严格反应产生的“痕迹”。

Antibiotic Scars Left on the Gut Microbiota from the Stringent Response.

机构信息

Department of Biomedical Sciences, College of Medicine, Korea University, Anam-Dong, Seongbuk-Gu, Seoul 136-705, Republic of Korea.

出版信息

Trends Microbiol. 2018 Sep;26(9):735-737. doi: 10.1016/j.tim.2018.06.003. Epub 2018 Jul 17.

DOI:10.1016/j.tim.2018.06.003

PMID:30025977

Abstract

Current research is primarily focused on compositional shifts and alterations in the metabolic status of the gut microbiota to elucidate the damage caused by antibiotics. However, the impact of the stringent response, which is governed by a global gene regulatory system conserved in most gut bacteria, should not be overlooked.

摘要

目前的研究主要集中在肠道微生物群的组成变化和代谢状态的改变上，以阐明抗生素造成的损害。然而，由大多数肠道细菌中保守的全局基因调控系统控制的严谨反应的影响不应被忽视。