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随机文化适应生活方式干预中的身体活动。

Physical Activity in a Randomized Culturally Adapted Lifestyle Intervention.

机构信息

Department of Clinical Sciences, Lund University, Malmö, Sweden.

Genetic and Molecular Epidemiology Unit, Department of Clinical Sciences, Lund University, Malmö, Sweden; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.

出版信息

Am J Prev Med. 2018 Aug;55(2):187-196. doi: 10.1016/j.amepre.2018.04.016.

Abstract

INTRODUCTION

Middle Eastern immigrants exhibit high levels of physical inactivity and are at an increased risk for Type 2 diabetes. The primary aim of this study was to examine the changes in objectively assessed physical activity levels following a culturally adapted lifestyle intervention program. The secondary aim was to examine the association between objectively assessed physical activity and insulin sensitivity.

STUDY DESIGN

RCT conducted over 4 months in 2015.

PARTICIPANTS

Iraqi immigrants residing in Malmö, Sweden, exhibiting one or more risk factors for Type 2 diabetes.

INTERVENTION

The intervention group (n=50) was offered a culturally adapted lifestyle intervention comprising seven group sessions including a cooking class. The control group (n=46) received usual care.

MAIN OUTCOME MEASURES

Raw accelerometry data were processed by validated procedures and daily mean physical activity intensity, vector magnitude high-pass filtered (VM-HPF), was inferred. Further inferences into the number of hours/day spent in sedentary (VM-HPF <48 milli-Gs [mGs] where G=9.8 m/sec) and light- (48- <163 mGs); moderate- (163- <420 mGs); and vigorous-intensity (≥420 mGs) activities were also calculated (year of analysis was 2016-2017).

RESULTS

No difference was observed between the two groups in terms of change over time in VM-HPF. There was a significant increase in the number of hours/day spent in light intensity physical activity in the intervention group compared with the control group (β=0.023, 95% CI=0.001, 0.045, p=0.037). The intervention group also increased the time spent in sedentary activities, with the highest VM-HPF (36- <48 mGs) within the sedentary behavior (B=0.022, 95% CI=0.002, 0.042, p=0.03). Higher VM-HPF was significantly associated with a higher insulin sensitivity index (β=0.014, 95% CI=0.0004, 0.025, p=0.007).

CONCLUSIONS

The findings favor the culturally adapted intervention approach for addressing low physical activity levels among Middle Eastern immigrants. Replacing sedentary time with light-intensity activities could be an achievable goal and will have potential beneficial effects for diabetes prevention among this sedentary group of immigrants.

TRIAL REGISTRATION

This study was registered at www.clinicaltrials.gov NCT01420198.

摘要

简介

中东移民的身体活动水平普遍较低,患 2 型糖尿病的风险增加。本研究的主要目的是检测经过文化适应性生活方式干预后,身体活动水平的变化。次要目的是检测身体活动与胰岛素敏感性之间的关系。

研究设计

2015 年进行的 4 个月 RCT。

参与者

居住在瑞典马尔默的有一个或多个 2 型糖尿病风险因素的伊拉克移民。

干预

干预组(n=50)接受了文化适应性生活方式干预,包括 7 次小组课程,其中包括烹饪课。对照组(n=46)接受常规护理。

主要观察指标

原始加速计数据经过验证程序处理,推断出日常平均体力活动强度向量幅度高通滤波(VM-HPF)。进一步推断出每天花费在久坐(VM-HPF<48 毫高斯(mGs),其中 G=9.8 米/秒)和轻(48-<163 mGs);中(163-<420 mGs);以及剧烈强度(≥420 mGs)活动的时间(分析年份为 2016-2017 年)。

结果

两组间 VM-HPF 的变化无差异。与对照组相比,干预组每天花在轻强度体力活动上的时间显著增加(β=0.023,95%CI=0.001,0.045,p=0.037)。干预组还增加了久坐活动的时间,最高的 VM-HPF(36-<48 mGs)在久坐行为内(B=0.022,95%CI=0.002,0.042,p=0.03)。更高的 VM-HPF 与更高的胰岛素敏感性指数显著相关(β=0.014,95%CI=0.0004,0.025,p=0.007)。

结论

这些发现支持针对中东移民低身体活动水平的文化适应性干预方法。用低强度活动取代久坐时间可能是一个可行的目标,并将对这群久坐移民的糖尿病预防产生潜在的有益影响。

试验注册

本研究在 www.clinicaltrials.gov 注册,编号为 NCT01420198。

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