Department of Clinical Sciences, Lund University, Malmö, Sweden.
Genetic and Molecular Epidemiology Unit, Department of Clinical Sciences, Lund University, Malmö, Sweden; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.
Am J Prev Med. 2018 Aug;55(2):187-196. doi: 10.1016/j.amepre.2018.04.016.
Middle Eastern immigrants exhibit high levels of physical inactivity and are at an increased risk for Type 2 diabetes. The primary aim of this study was to examine the changes in objectively assessed physical activity levels following a culturally adapted lifestyle intervention program. The secondary aim was to examine the association between objectively assessed physical activity and insulin sensitivity.
RCT conducted over 4 months in 2015.
Iraqi immigrants residing in Malmö, Sweden, exhibiting one or more risk factors for Type 2 diabetes.
The intervention group (n=50) was offered a culturally adapted lifestyle intervention comprising seven group sessions including a cooking class. The control group (n=46) received usual care.
Raw accelerometry data were processed by validated procedures and daily mean physical activity intensity, vector magnitude high-pass filtered (VM-HPF), was inferred. Further inferences into the number of hours/day spent in sedentary (VM-HPF <48 milli-Gs [mGs] where G=9.8 m/sec) and light- (48- <163 mGs); moderate- (163- <420 mGs); and vigorous-intensity (≥420 mGs) activities were also calculated (year of analysis was 2016-2017).
No difference was observed between the two groups in terms of change over time in VM-HPF. There was a significant increase in the number of hours/day spent in light intensity physical activity in the intervention group compared with the control group (β=0.023, 95% CI=0.001, 0.045, p=0.037). The intervention group also increased the time spent in sedentary activities, with the highest VM-HPF (36- <48 mGs) within the sedentary behavior (B=0.022, 95% CI=0.002, 0.042, p=0.03). Higher VM-HPF was significantly associated with a higher insulin sensitivity index (β=0.014, 95% CI=0.0004, 0.025, p=0.007).
The findings favor the culturally adapted intervention approach for addressing low physical activity levels among Middle Eastern immigrants. Replacing sedentary time with light-intensity activities could be an achievable goal and will have potential beneficial effects for diabetes prevention among this sedentary group of immigrants.
This study was registered at www.clinicaltrials.gov NCT01420198.
中东移民的身体活动水平普遍较低,患 2 型糖尿病的风险增加。本研究的主要目的是检测经过文化适应性生活方式干预后,身体活动水平的变化。次要目的是检测身体活动与胰岛素敏感性之间的关系。
2015 年进行的 4 个月 RCT。
居住在瑞典马尔默的有一个或多个 2 型糖尿病风险因素的伊拉克移民。
干预组(n=50)接受了文化适应性生活方式干预,包括 7 次小组课程,其中包括烹饪课。对照组(n=46)接受常规护理。
原始加速计数据经过验证程序处理,推断出日常平均体力活动强度向量幅度高通滤波(VM-HPF)。进一步推断出每天花费在久坐(VM-HPF<48 毫高斯(mGs),其中 G=9.8 米/秒)和轻(48-<163 mGs);中(163-<420 mGs);以及剧烈强度(≥420 mGs)活动的时间(分析年份为 2016-2017 年)。
两组间 VM-HPF 的变化无差异。与对照组相比,干预组每天花在轻强度体力活动上的时间显著增加(β=0.023,95%CI=0.001,0.045,p=0.037)。干预组还增加了久坐活动的时间,最高的 VM-HPF(36-<48 mGs)在久坐行为内(B=0.022,95%CI=0.002,0.042,p=0.03)。更高的 VM-HPF 与更高的胰岛素敏感性指数显著相关(β=0.014,95%CI=0.0004,0.025,p=0.007)。
这些发现支持针对中东移民低身体活动水平的文化适应性干预方法。用低强度活动取代久坐时间可能是一个可行的目标,并将对这群久坐移民的糖尿病预防产生潜在的有益影响。
本研究在 www.clinicaltrials.gov 注册,编号为 NCT01420198。