Albalawi Ibrahim Altedlawi
Associate Professor of Surgical Oncology, Department of Surgery, Faculty of Medicine, University of Tabuk, Saudi Arabia.
Electron Physician. 2018 Jun 25;10(6):6951-6955. doi: 10.19082/6951. eCollection 2018 Jun.
Phyllodes tumor is a benign breast cancer with a malignant potential. It is very rare in Saudi Arabia and also rare around the world. Malignant phyllodes tumors originate from the connective tissue of the breast, so they are histologically sarcomas. We report the largest phyllodes tumor ever seen in Saudi Arabia, a 41-year-old female who presented with a huge breast mass occupying the whole breast with areas of ulceration. Her history had started 14 months previously with a slowly growing left breast swelling, ultimately the lump ulcerated and became necrotic. Mastectomy with partial resection of the pectoral muscles was done. The tumor specimen measured exactly 30×20×13 cm in size, and weight of 5.4 kg, and with the closest margin of resection 0.5 cm away from the tumor the histopathology report came back as malignant phyllodes tumor. The patient was sent for radiotherapy and chemotherapy. We concluded that accurate preoperative pathological diagnosis is very important for management of phyllodes tumor, and allows correct surgical planning and avoidance of reoperation.
叶状肿瘤是一种具有恶性潜能的良性乳腺癌。它在沙特阿拉伯非常罕见,在世界范围内也很罕见。恶性叶状肿瘤起源于乳腺的结缔组织,因此在组织学上属于肉瘤。我们报告了沙特阿拉伯有史以来发现的最大的叶状肿瘤,一名41岁女性,她出现了一个巨大的乳腺肿块,占据了整个乳房,并伴有溃疡区域。她的病史始于14个月前,左乳房出现缓慢生长的肿胀,最终肿块发生溃疡并坏死。进行了乳房切除术并部分切除胸肌。肿瘤标本尺寸精确为30×20×13厘米,重5.4千克,切除边缘距肿瘤最近处为0.5厘米,组织病理学报告显示为恶性叶状肿瘤。该患者被送去接受放疗和化疗。我们得出结论,准确的术前病理诊断对于叶状肿瘤的治疗非常重要,有助于正确的手术规划并避免再次手术。