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65岁以上患者的孤立性主动脉瓣置换术。

Isolated aortic valve replacement in patients older than 65 years.

作者信息

Copeland J G, Griepp R B, Stinson E B, Shumway N E

出版信息

JAMA. 1977 Apr 11;237(15):1578-81.

PMID:300438
Abstract

The results of 196 isolated aortic valve replacements in patients older than 65 years were analyzed. Eighty-four percent of patients were in New York Heart Association (NYHA) functional class III or IV preoperatively. The operative mortality was 12% for all cases and 9% for elective cases. Actuarial probability of five-year survival was 55% for the entire group and 61% for discharged patients. Myocardial failure and congestive heart failure were the most common causes of early and late postoperative death, respectively. Embolic strokes occurred in 16% of discharged patients and caused substantial disability in 9%. At the termination of the study, 94% of surviving patients were in NYHA class I or II, and none were in class IV. Aortic valve replacement in elderly patients entails reasonable operative risk, and results in satisfactory postoperative rehabilitation.

摘要

分析了196例65岁以上患者行主动脉瓣置换术的结果。84%的患者术前纽约心脏协会(NYHA)心功能分级为III或IV级。所有病例的手术死亡率为12%,择期手术病例为9%。整个组的5年生存率精算概率为55%,出院患者为61%。心肌衰竭和充血性心力衰竭分别是术后早期和晚期死亡的最常见原因。16%的出院患者发生栓塞性卒中,其中9%导致严重残疾。在研究结束时,94%的存活患者NYHA分级为I或II级,无IV级患者。老年患者行主动脉瓣置换术手术风险合理,术后康复效果满意。

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