Di Labbio Giuseppe, Kadem Lyes
Laboratory of Cardiovascular Fluid Dynamics (LCFD), Department of Mechanical, Industrial and Aerospace Engineering, Concordia University, Montréal, Québec, Canada.
Laboratory of Cardiovascular Fluid Dynamics (LCFD), Department of Mechanical, Industrial and Aerospace Engineering, Concordia University, Montréal, Québec, Canada.
J Biomech. 2018 Sep 10;78:155-160. doi: 10.1016/j.jbiomech.2018.07.023. Epub 2018 Jul 17.
Unnatural dynamics of the notorious vortex in the left ventricle is often associated with cardiac disease. Understanding how different cardiac diseases alter the flow physics in the left ventricle may therefore provide a powerful tool for disease detection. In this work, the fluid dynamics in the left ventricle subject to different severities of aortic regurgitation is experimentally investigated by performing time-resolved particle image velocimetry in a left heart duplicator. Diastolic vortex reversal was observed in the left ventricle accompanied by an increase in viscous energy dissipation. Vortex dynamics and energy dissipation may provide useful insights on sub-optimal flow patterns in the left ventricle.
左心室中臭名昭著的涡流的异常动力学通常与心脏病有关。因此,了解不同的心脏病如何改变左心室中的流体物理特性可能为疾病检测提供一个强大的工具。在这项工作中,通过在左心模拟器中进行时间分辨粒子图像测速实验,对不同严重程度主动脉瓣反流情况下左心室内的流体动力学进行了研究。在左心室中观察到舒张期涡流反转,同时粘性能量耗散增加。涡流动力学和能量耗散可能为左心室中次优流动模式提供有用的见解。