CeNGEN 项目：整个神经系统的完整基因表达图谱。
The CeNGEN Project: The Complete Gene Expression Map of an Entire Nervous System.
机构信息
Departments of Genetics and Neuroscience, Yale University School of Medicine, New Haven, CT, USA.
Department of Biological Sciences, Columbia University, New York, New York, USA; Howard Hughes Medical Institute.
出版信息
Neuron. 2018 Aug 8;99(3):430-433. doi: 10.1016/j.neuron.2018.07.042.
Abstract
Differential gene expression defines individual neuron types and determines how each contributes to circuit physiology and responds to injury and disease. The C. elegans Neuronal Gene Expression Map & Network (CeNGEN) will establish a comprehensive gene expression atlas of an entire nervous system at single-neuron resolution.
摘要
差异基因表达定义了单个神经元类型，并决定了每个神经元类型如何对电路生理学做出贡献以及如何对损伤和疾病做出反应。秀丽隐杆线虫神经元基因表达图谱和网络 (CeNGEN) 将建立一个具有单细胞分辨率的整个神经系统的全面基因表达图谱。
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