Tripathy Jaya Prasad
International Union Against Tuberculosis and Lung Disease, The Union South East Asia Office, New Delhi, India,
International Union Against Tuberculosis and Lung Disease, Paris, France,
Diabetes Metab Syndr Obes. 2018 Jul 31;11:381-387. doi: 10.2147/DMSO.S157376. eCollection 2018.
Diabetes, hyperglycemia, and their complications are a growing problem in India. However, no comprehensive picture of this disease burden has yet been presented to date.
I used aggregate data from the Global Burden of Disease 2016 to describe the burden of diabetes and its risk factors, chronic kidney disease (CKD) due to diabetes, and diseases caused by high fasting plasma glucose from 1990 to 2016 in India.
Deaths due to diabetes accounted for 3.1% (95% uncertainty interval [UI]: 2.9-3.3) of all deaths in India in 2016, up from 0.98% (95% UI: 0.87-1.1) of all deaths in 1990. Diabetes and hyperglycemia accounted for 27.5 million disability-adjusted life years in 2016, of which diabetes accounted for 10 million. Diabetes contributes to the causation of ischemic heart disease, stroke, CKD, peripheral artery disease, specific cancers, and tuberculosis via intermediate hyperglycemia. High body mass index, dietary factors (diet low in fruits, nuts and seeds, and whole grains), and tobacco use were the most important risk factors for diabetes.
Diabetes and CKD due to hyperglycemia pose a large and increasing burden in India. Urgent programs and policies are needed to reduce the identified risk factors for diabetes and its burden.
糖尿病、高血糖及其并发症在印度正成为一个日益严重的问题。然而,迄今为止尚未有关于这种疾病负担的全面情况介绍。
我使用了《2016年全球疾病负担》的汇总数据,来描述1990年至2016年印度糖尿病及其危险因素、糖尿病所致慢性肾脏病(CKD)以及空腹血糖升高所致疾病的负担。
2016年,糖尿病导致的死亡占印度所有死亡人数的3.1%(95%不确定区间[UI]:2.9 - 3.3),高于1990年占所有死亡人数的0.98%(95% UI:0.87 - 1.1)。2016年,糖尿病和高血糖导致2750万伤残调整生命年(DALY),其中糖尿病导致1000万。糖尿病通过中间环节高血糖导致缺血性心脏病、中风、CKD、外周动脉疾病、特定癌症和结核病等疾病。高体重指数、饮食因素(水果、坚果和种子以及全谷物含量低的饮食)和吸烟是糖尿病最重要的危险因素。
高血糖所致糖尿病和CKD在印度造成了巨大且不断增加负担负担。需要紧急制定方案和政策来降低已确定的糖尿病危险因素及其负担。