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新型 Rhythmia©高密度标测系统在 400 名电生理患者中的初步单中心应用经验。

Initial single centre experience with the novel Rhythmia© high density mapping system in an all comer collective of 400 electrophysiological patients.

机构信息

Department of Medicine I, University Hospital Munich, Ludwig Maximilians University, Munich, Germany.

Department of Medicine I, University Hospital Munich, Ludwig Maximilians University, Munich, Germany.

出版信息

Int J Cardiol. 2018 Dec 1;272:168-174. doi: 10.1016/j.ijcard.2018.07.141. Epub 2018 Aug 2.

Abstract

BACKGROUND

A novel, automatically annotating ultra-high density mapping system (Rhythmia©, Boston Scientific) collects a high number and quality of electrograms (EGMs). So far, data on general use in the electrophysiological laboratory are sparse.

METHODS

We retrospectively analyzed all our ablations using Rhythmia and recorded patient clinical data, procedural parameters, and mapping parameters including the count of EGMs, mapping time, and mapping volume. Where appropriate, procedural parameters were compared over time to assess a learning curve.

RESULTS

400 patients underwent ablation of atrial fibrillation (n = 202), typical (n = 16) or atypical atrial flutter (n = 49), VT (n = 48), PVC (n = 35), accessory pathways (n = 14), AVNRT (n = 4), and focal atrial tachycardia (n = 32). System use was feasible, as no procedure had to be stopped for technical reasons and no ablation had to be withheld because of mapping failure, and safe, with an overall complication rate of 2.25%. Initial restrictions in manoeuvrability of the mapping catheter were overcome rapidly, as indicated by a significant decrease of fluoroscopy time (20 vs. 14 min, p = 0.02), use of contrast agent (50 vs. 40 ml; p < 0.01), and (not significant) lower procedure times (194 vs. 170 min; p = 0.12; comparing the first with the last third of patients undergoing pulmonary vein isolation only procedure). Ablation of complex left atrial, focal and ventricular tachycardias benefited from the reliable automatic annotation of a high number of EGMs.

CONCLUSION

The use of the Rhythmia is feasible and safe. Initial restrictions in manoeuvrability of the Orion mapping catheter were overcome rapidly. The procedures that benefit the most from ultra-high density mapping are complex left atrial tachycardias, focal tachycardias, and ventricular tachycardias.

摘要

背景

一种新型的自动标注超高密度标测系统(波士顿科学公司的 Rhythmia)可以采集大量高质量的电图(EGM)。到目前为止,关于该系统在电生理实验室中的常规应用的数据还很少。

方法

我们回顾性分析了使用 Rhythmia 进行的所有消融手术,并记录了患者的临床数据、手术参数以及标测参数,包括 EGM 数量、标测时间和标测体积。在适当的情况下,我们比较了不同时间段的手术参数,以评估学习曲线。

结果

400 名患者接受了房颤(n=202)、典型(n=16)或非典型房扑(n=49)、VT(n=48)、PVC(n=35)、旁路(n=14)、AVNRT(n=4)和局灶性房性心动过速(n=32)的消融治疗。该系统的使用是可行的,因为没有因为技术原因而停止手术,也没有因为标测失败而不得不放弃消融治疗,并且是安全的,总并发症发生率为 2.25%。标测导管的可操作性最初受到限制,但很快就得到了克服,这表现在透视时间(20 分钟对 14 分钟,p=0.02)、造影剂用量(50 毫升对 40 毫升;p<0.01)和(无统计学意义)手术时间(194 分钟对 170 分钟;p=0.12;比较仅行肺静脉隔离的前 1/3 和后 2/3 名患者)的显著减少。复杂左房、局灶性和室性心动过速的消融治疗得益于大量可靠的自动 EGM 标注。

结论

使用 Rhythmia 是可行和安全的。Orion 标测导管最初在可操作性方面受到的限制很快就得到了克服。超高密度标测最受益的是复杂左房性心动过速、局灶性心动过速和室性心动过速。

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