Guzelburc Vahit, Baran Caner, Yafi Faysal A, Cakir Asli, Kiremit Murat Can, Boz Mustafa Yucel, Horuz Rahim, Guven Selcuk, Hellstrom Wayne J G, Albayrak Selami
Department of Urology, Medical Faculty of Medipol University, Istanbul, Turkey.
Department of Urology, Adana Cukurova Askim Tufekci State Hospital, Adana, Turkey.
Int J Impot Res. 2019 Jan;31(1):20-24. doi: 10.1038/s41443-018-0066-y. Epub 2018 Aug 28.
Vasectomy is a popular and effective male surgical contraceptive method. Different techniques have been proposed to reduce failure rates and complications. In this study, we sought to compare vas deferens occlusion rates using both standard occlusion techniques and LigaSure (LSVS) for vasectomy.
A total of nine patients underwent open radical retropubic prostatectomy at our institution. During the procedure, a total of 125 fresh vas deferens samples were obtained and divided into four groups as follows: Group 1: ligation (n = 22), Group 2; ligation and electrocauterization (n = 18), Group 3; 5 mm LSVS (n = 44), Group 4; 10 mm LSVS (n = 41). All specimens were harvested during surgery and subsequent histopathological assessments were performed to assess the luminal status of the vas deferens.
Histopathological evaluation revealed that the majority of vas lumens with LSVS (79.5% of Group 3 and 89.4% of Group 4) were totally occluded. With standard techniques, however, the majority of vas lumens (86.4 and 77.8% of Groups 1 and 2, respectively) maintained a tiny patency.
On histopathological review, the application of LSVS resulted in better occlusion rates, compared to standard ligation methods. These findings suggest a higher occlusive role for LSVS for vasectomy. Further clinical studies are needed to confirm the clinical efficacy and safety of this technique.
输精管结扎术是一种常用且有效的男性外科避孕方法。人们提出了不同技术以降低失败率和并发症。在本研究中,我们试图比较输精管结扎术采用标准结扎技术和结扎速血管闭合系统(LSVS)时的输精管闭塞率。
共有9例患者在我院接受了开放性耻骨后根治性前列腺切除术。手术过程中,共获取125个新鲜输精管样本,并分为以下四组:第1组:结扎(n = 22),第2组:结扎加电灼(n = 18),第3组:5毫米LSVS(n = 44),第4组:10毫米LSVS(n = 41)。所有样本均在手术中采集,并进行后续组织病理学评估以评估输精管的管腔状态。
组织病理学评估显示,采用LSVS时,大多数输精管管腔(第3组为79.5%,第4组为89.4%)完全闭塞。然而,采用标准技术时,大多数输精管管腔(第1组和第2组分别为86.4%和77.8%)保持微小通畅。
组织病理学检查显示,与标准结扎方法相比,LSVS的应用导致更好的闭塞率。这些发现表明LSVS在输精管结扎术中具有更高的闭塞作用。需要进一步的临床研究来证实该技术的临床疗效和安全性。