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板层角膜移植术中的新月形折叠术——一例晚期透明边缘角膜变性病例中的新技术

Crescentic Tuck in Lamellar Keratoplasty-A Novel Technique in a Case of Advanced Pellucid Marginal Corneal Degeneration.

作者信息

Arora Ritu, Manudhane Aditi, Jain Parul, Goyal Jawahar Lal

机构信息

Department of Ophthalmology, Guru Nanak Eye Centre (R.A., J.L.G.), Affiliated to Maulana Azad Medical College, New Delhi, India; Tirupati Eye Centre (A.M.), Noida, Uttar Pradesh, India; and I CARE Hospital and Post Graduate Research Institute (P.J.), Noida, Uttar Pradesh, India.

出版信息

Eye Contact Lens. 2018 Sep;44 Suppl 1:S345-S347. doi: 10.1097/ICL.0000000000000352.

Abstract

PURPOSE

To describe a new surgical technique "crescentic tuck in lamellar keratoplasty" for the management of advanced pellucid marginal corneal degeneration (PMCD).

METHODS

A 45-year-old man with advanced PMCD and maximal thinning in the inferior juxtalimbal periphery underwent a crescentic lamellar keratoplasty in the right eye. Best-corrected visual acuity was 6/60 with no further improvement because of severe irregular astigmatism. Thinnest pachymetry in the peripheral cornea was 280 μm. Peripheral crescent-shaped lamellar corneal dissection of 3.5-mm width was performed, and an intrastromal pocket was fashioned from 4 to 8 O'clock, extending beyond limbus. A crescent-shaped donor corneal button of 3.5-mm width was denuded of its endothelium and beveled in inferior periphery to create a flange. The flange was tucked into the peripheral scleral pocket. The donor graft was secured to the host bed using 10-0 nylon interrupted sutures.

RESULTS

Donor cornea integrated with the host bed over time and best spectacle-corrected visual acuity at 1 year improved to 6/9 with -1.25/-3.5 D × 90°. The simK (simulated keratometry) changed from 41.6/56.3 diopters (D) to 45.1/50.6 D. The astigmatism reduced from 14.6 D to 5.5 D.

CONCLUSION

Crescentic tuck in lamellar keratoplasty provides good apposition of the donor lenticule and tectonic support to the peripheral thin cornea while preserving the peripheral limbal stem cells. Additionally, there is a significant reduction in the astigmatism, resulting in visual improvement.

摘要

目的

描述一种用于治疗晚期透明边缘角膜变性(PMCD)的新手术技术“新月形嵌入板层角膜移植术”。

方法

一名45岁患有晚期PMCD且下角膜缘周边部极度变薄的男性接受了右眼新月形板层角膜移植术。其最佳矫正视力为6/60,因严重不规则散光而无进一步改善。周边角膜最薄处厚度为280μm。进行了宽度为3.5mm的周边新月形板层角膜剖切,并在4点至8点制作了一个基质内袋,延伸至角膜缘外。一个宽度为3.5mm的新月形供体角膜片去除其内皮,并在下角膜缘周边部进行斜面处理以形成一个边缘。将该边缘嵌入周边巩膜袋中。使用10-0尼龙间断缝线将供体移植物固定于受体床。

结果

随着时间推移,供体角膜与受体床整合,1年后最佳眼镜矫正视力提高到6/9,散光度数为-1.25/-3.5 D×90°。模拟角膜曲率(simK)从41.6/56.3屈光度(D)变为45.1/50.6 D。散光从14.6 D降至5.5 D。

结论

新月形嵌入板层角膜移植术能使供体晶状体与周边薄角膜良好贴合,并为其提供结构性支撑,同时保留周边角膜缘干细胞。此外,散光显著降低,视力得到改善。

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