寄生虫外泌体在宿主-寄生虫相互作用中的作用。
Helminth extracellular vesicles in host-parasite interactions.
机构信息
Institute of Parasitology, University of Zurich, Winterthurerstrasse 266a, CH-8057 Zurich, Switzerland.
Institute of Parasitology, McGill University, 21111 Lakeshore Road, Ste-Anne-de-Bellevue, QC H9X 3V9, Canada.
出版信息
Curr Opin Microbiol. 2018 Dec;46:73-79. doi: 10.1016/j.mib.2018.08.002. Epub 2018 Aug 30.
Extracellular vesicles (EVs) have been characterized from many species of parasitic helminths, and recent experimental evidence supports important functions for their cargo in host-parasite relationships as immunomodulatory mediators. Here we summarize available data on the effects of parasite-derived EVs, including their protein and/or small RNA contents, on their hosts.
外泌体 (EVs) 已从许多种寄生蠕虫中得到了描述，最近的实验证据支持了它们在宿主-寄生虫关系中作为免疫调节介质的货物的重要功能。在这里，我们总结了有关寄生虫衍生的 EV 的影响的现有数据，包括它们的蛋白质和/或小 RNA 含量，对其宿主的影响。
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