ChEM-H Institute, Stanford University, Stanford, CA 94305, USA.
Cell. 2018 Sep 20;175(1):10-13. doi: 10.1016/j.cell.2018.08.031. Epub 2018 Sep 11.
This year's Lasker Clinical Research Award goes to James Baird Glen for the discovery and development of the anesthetic propofol. Patients benefit from its fast onset and rapid systemic clearance, eliminating the prolonged sedation effects experienced with earlier agents. In just 30 years, propofol has been adopted around the world for safe and controlled induction of anesthesia.
今年的拉斯克临床医学研究奖授予詹姆斯·贝尔德·格伦,以表彰他发现并开发了麻醉性异丙酚。患者受益于其起效迅速和快速全身清除,消除了早期药物带来的长时间镇静作用。仅仅 30 年,异丙酚就在全球范围内被采用,用于安全和可控的麻醉诱导。