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电子烟使用与美国人群有害酒精消费风险。

Electronic Cigarette Use and Risk of Harmful Alcohol Consumption in the U.S. Population.

机构信息

Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut.

出版信息

Alcohol Clin Exp Res. 2018 Dec;42(12):2385-2393. doi: 10.1111/acer.13889. Epub 2018 Oct 4.

Abstract

BACKGROUND

Electronic cigarette (e-cigarette) use is an increasingly common method of nicotine delivery in the general population. It is well-established that tobacco users are at increased risk to engage in hazardous drinking and meet criteria for alcohol use disorder (AUD) relative to nonusers. Less is known, however, about the risk of harmful alcohol use among people who use e-cigarettes. The current study reports on the association between e-cigarette and alcohol use in the U.S. population using a nationally representative sample.

METHODS

Data from 36,309 adults who participated in the National Epidemiologic Survey on Alcohol and Related Conditions-Wave III were included in the study. The Alcohol Use Disorder and Associated Disabilities Interview Schedule (AUDADIS) measured past-year e-cigarette and alcohol use outcomes. Based on past-year e-cigarette use, respondents were categorized as nonusers, nondaily users, or daily users. Alcohol use outcomes were drinking quantity/frequency, binge drinking frequency, AUD diagnostic status, and National Institute on Alcohol Abuse and Alcoholism-defined hazardous drinking status.

RESULTS

Controlling for demographic characteristics, daily and nondaily e-cigarette users showed increased risk of harmful alcohol use compared to e-cigarette nonusers, including hazardous drinking (adjusted odds ratios [AORs] = 1.69; 2.48), AUD (AORs = 1.89; 2.44), and binge drinking frequency (AORs = 1.30 to 3.30). Nondaily e-cigarette use was associated with higher levels of risk than was daily use. Secondary analyses examined alcohol use outcomes according to participants' patterns of dual tobacco cigarette/e-cigarette use. These analyses confirmed that e-cigarette use alongside tobacco cigarette use is associated with additive risk of harmful alcohol consumption, particularly among nondaily users.

CONCLUSIONS

E-cigarette users, particularly those who engage in nondaily and dual use, show elevated rates of harmful alcohol use. Heavy drinking may constitute a source of health risk among e-cigarette users.

摘要

背景

电子烟(e-cigarette)的使用在普通人群中是一种越来越常见的尼古丁输送方式。已证实,与非使用者相比,烟草使用者有更高的风险从事危险饮酒并符合酒精使用障碍(AUD)的标准。然而,人们对使用电子烟者中有害酒精使用的风险知之甚少。本研究使用具有全国代表性的样本报告了美国人群中电子烟和酒精使用之间的关联。

方法

本研究纳入了参与国家酒精流行病学调查与相关条件-第三波(National Epidemiologic Survey on Alcohol and Related Conditions-Wave III)的 36309 名成年人的数据。酒精使用障碍和相关残疾访谈表(Alcohol Use Disorder and Associated Disabilities Interview Schedule,AUDADIS)测量了过去一年的电子烟和酒精使用结果。根据过去一年的电子烟使用情况,受访者被分为非使用者、非每日使用者或每日使用者。酒精使用结果包括饮酒量/频率、狂饮频率、AUD 诊断状况以及国家酒精滥用和酒精中毒研究所定义的危险饮酒状况。

结果

控制人口统计学特征后,与电子烟非使用者相比,每日和非每日电子烟使用者表现出更高的有害酒精使用风险,包括危险饮酒(调整后的优势比 [adjusted odds ratios,AOR] = 1.69;2.48)、AUD(AORs = 1.89;2.44)和狂饮频率(AORs = 1.30 至 3.30)。非每日电子烟使用者的风险水平高于每日使用者。次要分析根据参与者的双重烟草香烟/电子烟使用模式检查了酒精使用结果。这些分析证实,电子烟与烟草香烟同时使用与有害酒精消耗的附加风险相关,特别是在非每日使用者中。

结论

电子烟使用者,特别是那些从事非每日和双重使用者,表现出更高的有害酒精使用率。重度饮酒可能是电子烟使用者的健康风险来源。

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