Postgraduate Course Stress Management and Health Promotion, School of Medicine, National Kapodistrian University of Athens, Athens, Greece.
1st Department of Dermatology, "Andreas Syggros" Hospital, School of Medicine, National Kapodistrian University of Athens, Athens, Greece.
Int J Dermatol. 2019 Feb;58(2):218-220. doi: 10.1111/ijd.14227. Epub 2018 Sep 19.
Acne vulgaris (AV) is one of the most common disorders treated by dermatologists and other healthcare providers. Stress is a well-attested contributor to AV pathogenesis. However, to our knowledge, stress management has not yet been performed in AV patients. In this 8-week experimental study, we primarily examined the effectiveness of a novel method, dubbed Pythagorean Self-Awareness Intervention (PSAI) in AV.
This is a two-armed 1 : 1 randomized non-blind experimental study. The total sample was comprised of 15 female patients in the intervention group (mean age 27.2 ± 6.6) and 15 female patients in the control group (mean age 29.1 ± 6.9), all women. Measurements included clinical stage of AV, acne-related quality of life, perceived stress, and positive and negative affect assessed by validated self-administered tools.
Fourteen (93.3%) patients in the intervention group and four (26.7%) patients in the control group showed improvement of the acne stage (relative risk: 3.5, 95% CI 1.5-8.2, P = 0.001). Significant improvements remained after adjusting for age and baseline acne stage. Large to moderate significant effects were observed for perceived stress and negative affect. There were no dropouts and side effects in the PSAI group, whereas compliance reached 100%.
Pythagorean Self-Awareness Intervention is a feasible and possibly effective stress management method for AV. Future larger and longer randomized controlled studies are strongly encouraged.
寻常痤疮(AV)是皮肤科医生和其他医疗保健提供者治疗的最常见疾病之一。压力是公认的 AV 发病机制的促成因素。然而,据我们所知,压力管理尚未在 AV 患者中进行。在这项为期 8 周的实验研究中,我们主要研究了一种新方法——毕达哥拉斯自我意识干预(PSAI)在 AV 中的有效性。
这是一项双臂 1:1 随机非盲实验研究。总样本包括干预组的 15 名女性患者(平均年龄 27.2 ± 6.6)和对照组的 15 名女性患者(平均年龄 29.1 ± 6.9),均为女性。测量包括 AV 的临床阶段、痤疮相关生活质量、感知压力以及通过经过验证的自我管理工具评估的积极和消极影响。
干预组的 14 名(93.3%)患者和对照组的 4 名(26.7%)患者的痤疮阶段有所改善(相对风险:3.5,95%CI 1.5-8.2,P = 0.001)。调整年龄和基线痤疮阶段后仍保持显著改善。感知压力和消极影响有较大到中度的显著效果。PSAI 组没有脱落和副作用,而依从性达到 100%。
毕达哥拉斯自我意识干预是一种可行且可能有效的 AV 压力管理方法。强烈鼓励未来进行更大规模和更长时间的随机对照研究。