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连通指纹:从地域描述到抽象空间。

Connectivity Fingerprints: From Areal Descriptions to Abstract Spaces.

机构信息

Wellcome Centre for Integrative Neuroimaging, Centre for Functional MRI of the Brain, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK; Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands.

Wellcome Centre for Integrative Neuroimaging, Department of Experimental Psychology, University of Oxford, Oxford, UK; Wellcome Centre for Human Neuroimaging, University College, London, London, UK.

出版信息

Trends Cogn Sci. 2018 Nov;22(11):1026-1037. doi: 10.1016/j.tics.2018.08.009. Epub 2018 Sep 18.

Abstract

Fifteen years ago, Passingham and colleagues proposed that brain areas can be described in terms of their unique pattern of input and output connections with the rest of the brain, and that these connections are a crucial determinant of their function. We explore how the advent of neuroimaging of connectivity has allowed us to test and extend this proposal. We show that describing the brain in terms of an abstract connectivity space, as opposed to physical locations of areas, provides a natural and powerful framework for thinking about brain function and its variation across the brains of individuals, populations, and species.

摘要

十五年前,Passingham 和他的同事们提出,大脑区域可以根据它们与大脑其余部分的独特输入和输出连接模式来描述,而这些连接是其功能的关键决定因素。我们探讨了连接性神经影像学的出现如何使我们能够检验和扩展这一观点。我们表明,用抽象的连接空间而不是区域的物理位置来描述大脑,为思考大脑功能及其在个体、群体和物种大脑中的变化提供了一个自然而强大的框架。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f62/6198109/ffaaf0c5f8af/gr1.jpg

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