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小儿肾手术中骶管阻滞与椎旁阻滞的比较:前瞻性随机、盲法临床试验。

Comparison of caudal epidural block with paravertebral block for renal surgeries in pediatric patients: A prospective randomised, blinded clinical trial.

机构信息

Department of Anaesthesiology, Pain Medicine and Critical Care, All India Institute of Medical Sciences, New Delhi, India.

Department of Anaesthesiology, Pain Medicine and Critical Care, All India Institute of Medical Sciences, New Delhi, India.

出版信息

J Clin Anesth. 2019 Feb;52:105-110. doi: 10.1016/j.jclinane.2018.09.007. Epub 2018 Sep 19.

Abstract

STUDY OBJECTIVE

This study was undertaken to compare the analgesic efficacy of ultrasound-guided single-shot caudal block with ultrasound-guided single-shot paravertebral block in children undergoing renal surgeries.

DESIGN

Randomised, interventional, blinded clinical trial.

SETTING

Operating rooms of All India Institute of Medical Sciences, New Delhi, India.

PATIENTS

50 children aged 2-10 years, of ASA status I/II, posted for elective renal surgeries.

INTERVENTIONS

The children were randomised into two groups (Group C-caudal block, Group P-paravertebral block). After induction of general anesthesia, single-shot caudal or paravertebral block was performed under ultrasound guidance, with 0.2% ropivacaine with 1:200000 adrenaline.

MEASUREMENTS

Time to first rescue analgesia, time to perform blocks, intraoperative and post-operative hemodynamics, post-operative FLACC scores, incidence of complications, parental satisfaction scores were recorded.

MAIN RESULTS

Children in Group P had significantly longer duration of analgesia (p < 0.0004) than Group C. Post-operative FLACC scores (p < 0.005) and analgesic requirements (p < 0.0004) were lower in Group P. The mean fentanyl requirement over 24 h in group P was 0.56 ± 0.82 μg/kg, compared to 1.8 ± 1.2 μg/kg in group C. Parents in Group P reported greater satisfaction (p < 0.02). No complications were seen in either of the groups.

CONCLUSION

This study showed superior analgesia and parental satisfaction with single-shot paravertebral block in comparison to single-shot caudal block for renal surgeries in children. However, the block performance in children requires adequate expertise and practice.

摘要

研究目的

本研究旨在比较超声引导单次骶管阻滞与超声引导单次椎旁阻滞在小儿肾手术中的镇痛效果。

设计

随机、干预、盲法临床试验。

地点

印度新德里全印医学科学研究所的手术室。

患者

50 名年龄在 2-10 岁、ASA 分级 I/II 的择期行肾手术的儿童。

干预措施

患儿随机分为两组(C 组-骶管阻滞,P 组-椎旁阻滞)。全身麻醉诱导后,在超声引导下进行单次骶管或椎旁阻滞,使用 0.2%罗哌卡因加 1:200000 肾上腺素。

测量

首次补救镇痛时间、完成阻滞时间、术中及术后血流动力学、术后 FLACC 评分、并发症发生率、家长满意度评分。

主要结果

P 组患儿的镇痛持续时间明显长于 C 组(p<0.0004)。P 组患儿术后 FLACC 评分(p<0.005)和镇痛需求(p<0.0004)均较低。P 组患儿 24 小时内芬太尼的平均需要量为 0.56±0.82μg/kg,而 C 组为 1.8±1.2μg/kg。P 组的家长报告了更高的满意度(p<0.02)。两组均未出现并发症。

结论

与单次骶管阻滞相比,单次椎旁阻滞在小儿肾手术中具有更好的镇痛效果和家长满意度。然而,儿童的阻滞操作需要足够的专业知识和实践经验。

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