Canestraro Julia, Sherman Jerome
SUNY College of Optometry, New York, NY, USA,
Department of Clinical Education, SUNY College of Optometry, New York, NY, USA.
Eye Brain. 2018 Sep 13;10:79-84. doi: 10.2147/EB.S160999. eCollection 2018.
The classic presentation of pigmentary dispersion syndrome (PDS) often consists of midperipheral iris transillumination defects, Krukenberg's spindle, and dense homogeneous trabecular pigmentation. Other subtle, sometimes overlooked features include pigment on the lens zonules, pigment on the anterior lens capsule and pigment along the equator of the posterior lens capsule.
This unique presentation of PDS presented with bilateral, dense, oblique, and symmetrical pigment deposition along the posterior lens capsule that changed in shape, density, and extent over the span of 3 years.
There have been few reports in the literature that describe a central accumulation of pigment along the posterior lens capsule associated with PDS. There are reported cases of pigment deposition along the central aspect of the posterior lens capsule, some changing over time, although none were bilateral and symmetrical. There are suggestions that perhaps this central pigment deposition is related to a break in the ligament of Weiger, allowing communication between the posterior chamber and posterior lens capsule. This is a case in which curvilinear, symmetrical, and changing pigment deposition on the posterior lens capsule is suggestive of perhaps another key features of PDS.
色素播散综合征(PDS)的典型表现通常包括中周部虹膜透照缺损、 Krukenberg梭和致密均匀的小梁色素沉着。其他细微的、有时被忽视的特征包括晶状体悬韧带色素沉着、晶状体前囊色素沉着以及晶状体后囊赤道部色素沉着。
该例独特的PDS表现为双侧沿晶状体后囊出现致密、倾斜且对称的色素沉着,在3年期间其形状、密度和范围发生了变化。
文献中很少有报道描述与PDS相关的沿晶状体后囊中央色素积聚情况。有报道称沿晶状体后囊中央出现色素沉着,部分随时间变化,但均非双侧对称。有观点认为这种中央色素沉着可能与Weiger韧带断裂有关,使得后房与晶状体后囊之间相通。此病例中,晶状体后囊上呈曲线状、对称且变化的色素沉着提示这可能是PDS的另一个关键特征。