非眼部贝赫切特病患者光学相干断层扫描血管造影特征的定量分析。
Quantitative Analysis of Optical Coherence Tomography Angiography Features in Patients with Nonocular Behcet's Disease.
机构信息
a Ulucanlar Eye Training and Research Hospital , Ankara , Turkey.
b Department of Rheumatology , Gülhane Training and Research Hospital , Ankara , Turkey.
出版信息
Curr Eye Res. 2019 Feb;44(2):212-218. doi: 10.1080/02713683.2018.1530361. Epub 2018 Oct 9.
PURPOSE
To quantitatively measure the flow, nonflow, density, and foveal avascular zone (FAZ) assessment tool parameters of optical coherence tomography angiography (OCTA) in patients with nonocular Behcet's Disease (BD), and to compare the results with those obtained in healthy controls.
METHODS
FAZ parameters, flow area of choriocapillaris, and vessel density values of both superficial (SCP) and deep capillary plexuses (DCP) were measured using OCTA.
RESULTS
The FAZ area in SCP, FAZ area in full retinal vasculature, and FAZ perimeter were significantly higher and foveal density-300 was significantly lower in the BD group than in the control group (p = 0.008, p = 0.015, p = 0.011, and p = 0.045, respectively). Vessel density of the foveal region in SCP and DCP were significantly lower in the BD group than in the control group (p = 0.039 and p = 0.010).
CONCLUSION
Lower capillary vessel densities, particularly in the foveal region, could be considered a subclinical form of ocular involvement in nonocular BD.
目的
定量测量非眼部贝赫切特病（BD）患者的光学相干断层扫描血管造影（OCTA）的血流、无血流、密度和中心凹无血管区（FAZ）评估工具参数，并将结果与健康对照组进行比较。
方法
使用 OCTA 测量脉络膜毛细血管的 FAZ 参数、血流面积和浅层（SCP）和深层毛细血管丛（DCP）的血管密度值。
结果
BD 组的 SCP 中 FAZ 面积、全视网膜血管 FAZ 面积和 FAZ 周长明显高于对照组（p=0.008、p=0.015、p=0.011 和 p=0.045），而 FAZ 密度-300 明显低于对照组（p=0.045）。BD 组 SCP 和 DCP 的中心凹区域血管密度明显低于对照组（p=0.039 和 p=0.010）。
结论
较低的毛细血管密度，特别是在中心凹区域，可被视为非眼部 BD 的眼部受累的亚临床形式。
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