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加纳两家地区医院临床试验的影响:加纳研究人员的观点

Impact of a Clinical Trial in Two District Hospitals in Ghana: Perspectives of Ghanaian Researchers.

作者信息

Wilson Patrick T, Giessler Katie, Morris Marilyn C

机构信息

1 Columbia University Medical Center, New York, NY, USA.

2 University of California, San Francisco, CA, USA.

出版信息

J Empir Res Hum Res Ethics. 2018 Dec;13(5):486-493. doi: 10.1177/1556264618804965. Epub 2018 Oct 8.

Abstract

Conducting clinical trials in resource-poor settings may contribute to local capacity building. We describe the perspectives of local research personnel regarding the impact of collaborating in a clinical trial in rural Ghana. Forty-six Ghanaian research personnel were eligible to complete an anonymous survey, and 35 (76%) participated. Of the 35 respondents, 32 (91%) agreed that future patients will benefit because the hospital was part of the study. All 35 respondents reported a personal benefit derived from study involvement, most commonly citing skills or knowledge gained. Of the 35 individuals, 21 reported one or more burdens, most commonly citing nonspecific research responsibilities. Our data support the hypothesis that participation in clinical trials can contribute to capacity building in district hospitals in a lower middle-income country.

摘要

在资源匮乏地区开展临床试验可能有助于当地能力建设。我们描述了当地研究人员对参与加纳农村地区一项临床试验的影响的看法。46名加纳研究人员有资格完成一项匿名调查,35人(76%)参与了调查。在35名受访者中,32人(91%)同意未来的患者将受益,因为该医院是研究的一部分。所有35名受访者都报告称从参与研究中获得了个人益处,最常提到的是获得的技能或知识。在这35人中,21人报告了一项或多项负担,最常提到的是非特定的研究职责。我们的数据支持这样一种假设,即参与临床试验有助于中低收入国家地区医院的能力建设。

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