神经系统发育：蝇类和线虫在神经元身份控制上趋同。
Nervous System Development: Flies and Worms Converging on Neuron Identity Control.
机构信息
Department of Neurobiology, University of Chicago, Chicago, IL 60637, USA.
Department of Biology, Howard Hughes Medical Institute, Columbia University, New York, NY 10027, USA.
出版信息
Curr Biol. 2018 Oct 8;28(19):R1154-R1157. doi: 10.1016/j.cub.2018.08.032.
PMID:30300603
Abstract
Distinct neuronal cell types display phenotypic similarities such as their neurotransmitter identity. Studies in worms and flies have revealed that this phenotypic convergence can be brought about by distinct transcription factors regulating the same effector genes in different neuron types.
摘要
不同的神经元细胞类型表现出相似的表型特征，例如它们的神经递质身份。在蠕虫和果蝇中的研究表明，这种表型趋同可以通过不同的转录因子在不同神经元类型中调节相同的效应基因来实现。
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