Huntsman Cancer Institute, 2000 Circle of Hope Drive, Salt Lake City, UT 84103, United States of America; Department of Radiation Oncology, University of Utah School of Medicine, 1950 Circle of Hope, Rm 1570, Salt Lake City, UT 84112, United States of America.
Huntsman Cancer Institute, 2000 Circle of Hope Drive, Salt Lake City, UT 84103, United States of America; Division of Public Health, Department of Family and Preventative Medicine, University of Utah School of Medicine, 375 Chipeta Way, Suite. A, Salt Lake City, UT 84108, United States of America.
Gynecol Oncol. 2018 Dec;151(3):547-554. doi: 10.1016/j.ygyno.2018.10.004. Epub 2018 Oct 6.
One woman dies from cervix cancer every 2 min, adding up to over 270,000 deaths globally per year. This cancer affects a young population, and hence, the loss of life is staggering. There are many aspects of prevention, screening, and care that are suboptimal. A great deal is known about HPV induced carcinogenesis, yet clinical outcomes have been stagnant over decades. There has been no improvement in cervix cancer survival in the US since the mid-1970s [1]. With increased knowledge of the disease and greater worldwide resources including prevention, screening, and improved therapeutics, there is significant promise for fewer women to die from this virally induced cancer. We focus here on the major problems in prevention, screening, and delivery of care for cervix cancer and provide concrete solutions. With appropriate focus, a major improvement in survival from cervix cancer could be achieved in a short time span.
每 2 分钟就有一名女性死于宫颈癌,全球每年因此死亡的人数超过 27 万。这种癌症影响到年轻人群,因此生命的损失令人震惊。在预防、筛查和护理方面存在许多不理想的地方。人们对 HPV 引起的癌变有了很多了解,但几十年来临床效果一直停滞不前。自 20 世纪 70 年代中期以来,美国宫颈癌的生存率没有提高[1]。随着对该疾病的了解不断增加,以及包括预防、筛查和改进治疗在内的全球资源的增加,有望减少更多女性死于这种病毒引起的癌症。我们在这里重点关注宫颈癌预防、筛查和护理方面的主要问题,并提供具体的解决方案。如果重点适当,宫颈癌的生存率在短时间内可能会得到显著提高。