Jagielski Mateusz, Smoczyński Marian, Adrych Krystian
Department of Gastroenterology and Hepatology, Medical University of Gdansk, Gdansk, Poland.
Prz Gastroenterol. 2018;13(3):242-248. doi: 10.5114/pg.2018.78290. Epub 2018 Sep 17.
In last three decades we have observed development in minimally invasive techniques in the treatment of walled-off pancreatic necrosis (WOPN). Endoscopic treatment of the consequences of acute necrotising pancreatitis is a accepted and common minimally invasive method.
Evaluation of the efficiency and safety of the innovative endoscopic treatment method (single transluminal gateway transcystic multiple drainage - SGTMD) in patients with extensive walled-off pancreatic necrosis.
The retrospective analysis of 114 consecutive patients with symptomatic WOPN, who were treated endoscopically in our medical centre between 2011 and 2016.
Single transluminal gateway transcystic multiple drainage was performed in 21/114 (18.42%) patients. Endoscopic necrosectomy under fluoroscopic guidance was performed in 12/21 (57.14%) patients. Complications of treatment appeared in 7/21 (33.33%) patients. The most common of complication was upper gastrointestinal bleeding treated conservatively with packed red blood cells transfusions. There were no deaths. Therapeutic success was reached in 20/21 (95.24%) patients. No patient required surgery. The medium time of follow-up was 22 months (16-47). During the observation the recurrence of pancreatic fluid collection was noticed in 1/21 (4.76%) patients. Long-term success of endoscopic treatment was achieved in 19/21 (90.47%) patients.
Single transluminal gateway transcystic multiple drainage is an effective method of endoscopic treatment for extensive walled-off pancreatic necrosis with an acceptable amount of complications. However, the method of interventional treatment of pancreatic necrosis should depend not only on the location of necrosis, but also on the experience of the medical centre.
在过去三十年中,我们观察到在治疗包裹性胰腺坏死(WOPN)方面微创技术的发展。内镜治疗急性坏死性胰腺炎的后果是一种被认可且常见的微创方法。
评估创新的内镜治疗方法(单腔经皮经囊肿多管引流术 - SGTMD)在广泛包裹性胰腺坏死患者中的有效性和安全性。
对2011年至2016年间在我们医疗中心接受内镜治疗的114例有症状的WOPN连续患者进行回顾性分析。
21/114(18.42%)例患者接受了单腔经皮经囊肿多管引流术。12/21(57.14%)例患者在荧光透视引导下进行了内镜坏死组织清除术。7/21(33.33%)例患者出现治疗并发症。最常见的并发症是上消化道出血,通过输注浓缩红细胞保守治疗。无死亡病例。20/21(95.24%)例患者治疗成功。无患者需要手术。中位随访时间为22个月(16 - 47个月)。观察期间,1/21(4.76%)例患者出现胰液积聚复发。19/21(90.47%)例患者内镜治疗获得长期成功。
单腔经皮经囊肿多管引流术是治疗广泛包裹性胰腺坏死的一种有效内镜治疗方法,并发症数量可接受。然而,胰腺坏死的介入治疗方法不仅应取决于坏死的位置,还应取决于医疗中心的经验。