颈动脉超声和超敏C反应蛋白在中国2型糖尿病合并急性心肌梗死患者中的诊断价值

Li Juan, Wang Liangliang, Wang Qian, Xin Zhaoqin, Liu Yilin, Zhao Qinghua

Special Inspection Department.

Ultrasound Department, Liaocheng People's Hospital, Shandong, China.

Medicine (Baltimore). 2018 Oct;97(41):e12334. doi: 10.1097/MD.0000000000012334.

Hypersensitive C-reactive protein (hs-CRP) is reported to be significant risk indicators not only for the development of cardiovascular disease, but also for the development or progression of type 2 diabetes. The objective of this study was to analyze the significance of hs-CRP in type 2 diabetes mellitus (T2DM) combined with acute myocardial infarction (AMI).Fifty patients with both T2DM and AMI, 50 patients with T2DM alone, and 50 healthy subjects (control group) were selected.Operating characteristic (ROC) analysis revealed that the sensitivity, specificity, accuracy, and critical value in the diagnosis of T2DM combined with AMI using hs-CRP level were 84.6%, 75.9%, 0.856, and 7.34 mg/L, respectively. For using vulnerable plaque rate, these were 92.7%, 95.3%, 0.923, and 0.52, respectively.hs-CRP play a significant role in the early diagnosis of T2DM combined with AMI.

据报道，超敏C反应蛋白（hs-CRP）不仅是心血管疾病发生的重要风险指标，也是2型糖尿病发生或进展的重要风险指标。本研究的目的是分析hs-CRP在2型糖尿病（T2DM）合并急性心肌梗死（AMI）中的意义。选取了50例T2DM合并AMI患者、50例单纯T2DM患者和50例健康受试者（对照组）。操作特征（ROC）分析显示，使用hs-CRP水平诊断T2DM合并AMI时的敏感性、特异性、准确性和临界值分别为84.6%、75.9%、0.856和7.34mg/L。使用易损斑块率时，这些指标分别为92.7%、95.3%、0.923和0.52。hs-CRP在T2DM合并AMI的早期诊断中起重要作用。