基于浦肯野图像对比度来测量角膜和晶状体散射的系统。
System based on the contrast of Purkinje images to measure corneal and lens scattering.
作者信息
Santos Pau, Martínez-Roda Juan A, Ondategui Juan C, Díaz-Doutón Fernando, Cazal Jorge A Ortiz, Vilaseca Meritxell
机构信息
Center for Sensors, Instruments and Systems Development (CD6), Universitat Politècnica de Catalunya (UPC), Rambla Sant Nebridi 10, Terrassa 08222, Barcelona, Spain.
Hospital CIMA Sanitas, Passeig Manuel Girona 33, Barcelona 08034, Barcelona, Spain.
出版信息
Biomed Opt Express. 2018 Sep 18;9(10):4907-4918. doi: 10.1364/BOE.9.004907. eCollection 2018 Oct 1.
Current methods to measure intraocular scattering provide information on the total scattered light, which consists of the combined contributions originating from different ocular structures. In this work, we propose a technique for the objective and independent assessment of scattering caused by the cornea and the lens based on the analysis of the contrast of the third and fourth Purkinje images. The technique is preliminarily validated first by using artificial eyes with different levels of corneal and lens scattering; second, it is validated in eyes wearing customized contact lenses to simulate corneal scattering and eyes with nuclear cataracts. Finally, it is tested on a larger population of eyes with cataracts and corneal disorders to prove its clinical usefulness.
当前测量眼内散射的方法可提供有关总散射光的信息，总散射光由源自不同眼部结构的综合贡献组成。在这项工作中，我们基于对第三和第四普尔钦耶图像对比度的分析，提出了一种用于客观且独立评估由角膜和晶状体引起的散射的技术。该技术首先通过使用具有不同角膜和晶状体散射水平的人工眼进行初步验证；其次，在佩戴定制隐形眼镜以模拟角膜散射的眼睛以及患有核性白内障的眼睛中进行验证。最后，在更多患有白内障和角膜疾病的眼睛群体上进行测试，以证明其临床实用性。
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