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多发性硬化症患病率研究:土耳其黑海和地中海地区3个沿海城市的比较

Multiple sclerosis prevalence study: The comparison of 3 coastal cities, located in the black sea and mediterranean regions of Turkey.

作者信息

Türk Börü Ülkü, Duman Arda, Kulualp Ahmet Şükrü, Güler Neşe, Taşdemir Mustafa, Yılmaz Ümit, Alp Recep, Bölük Cem

机构信息

University of Health Sciences Dr Lütfi Kırdar Kartal Research and Training Hospital.

Maltepe State Hospital.

出版信息

Medicine (Baltimore). 2018 Oct;97(42):e12856. doi: 10.1097/MD.0000000000012856.

Abstract

The prevalence of multiple sclerosis (MS) has significantly increased all over the world. Recent studies have shown that Turkey has quite a high prevalence. The aim of this study is to estimate prevalence in the Mediterranean and Black Sea regions of Turkey and to compare the results.This study was designed as a door to door survey in 3 cities. One is located in the Mediterranean region (South), 2 are located in the Black Sea region (North). A previous validated form was used for screening in the field. The patients were examined first in the field, then in the regional health facility. McDonald criteria were used for the diagnosis.In total, 26 patients were diagnosed with MS. The prevalence was found to be 18.6/100,000 in Artvin (Black Sea region), 55.5/100,000 in Ordu, (Black Sea region), 52.00/100,000 in Gazipaşa (Mediterranean region). The female/male ratio was 2.25.This study is the first prevalence study which was conducted in the Mediterranean City (South) of Turkey. The prevalence rate was found to be higher than expected in the Mediterranean city of Gazipaşa. The results showed that the prevalence varies from region to region. Latitude difference was not observed.

摘要

多发性硬化症(MS)在全球的患病率显著上升。近期研究表明,土耳其的患病率相当高。本研究旨在估算土耳其地中海和黑海地区的患病率并比较结果。

本研究设计为对3个城市进行挨家挨户的调查。其中一个位于地中海地区(南部),两个位于黑海地区(北部)。在实地筛查中使用了先前经过验证的表格。患者首先在实地接受检查,然后在地区卫生机构接受检查。诊断采用麦克唐纳标准。

总共26例患者被诊断为MS。阿尔特温(黑海地区)的患病率为18.6/10万,奥尔杜(黑海地区)为55.5/10万,加济帕夏(地中海地区)为52.00/10万。女性/男性比例为2.25。

本研究是在土耳其地中海城市(南部)进行的首次患病率研究。加济帕夏这座地中海城市的患病率高于预期。结果表明,患病率因地区而异。未观察到纬度差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6107/6211850/19a95f511f73/medi-97-e12856-g001.jpg

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