Yoshioka Nori, Deguchi Matsuo, Hagiya Hideharu, Kagita Masanori, Tomono Kazunori
Clin Lab. 2018 Oct 1;64(10):1791-1793. doi: 10.7754/Clin.Lab.2018.180518.
With the improvement in sanitation and hygiene, the incidence of hepatitis A virus (HAV) infection has declined, and its seroprevalence among Japanese people has been reduced. Universal HAV vaccination is yet to be implemented in Japan, and the healthcare workers (HCWs) are at higher risks of acquiring this infection. We herein report the seroepidemiology of HAV infection among HCWs at Osaka University Hospital.
Between September and October 2017, we collected serum samples submitted to our laboratory for HCWs health examination and tested for the anti-HAV antibody.
Overall HAV seropositivity rate was 5.1% (22/436 samples). The seroprevalence was higher among those in the twenties (6.0%) and thirties (8.0%), compared to older age groups.
In this age of internationalization, the decreasing immunity for HAV places HCWs at risk of developing the disease. As a preventive measure against occupational infection, HAV vaccination may be needed for Japanese HCWs.
随着环境卫生和个人卫生状况的改善，甲型肝炎病毒（HAV）感染的发病率有所下降，日本人中的血清阳性率也已降低。日本尚未实施普遍的HAV疫苗接种，医护人员（HCW）感染这种病毒的风险更高。我们在此报告大阪大学医院医护人员中HAV感染的血清流行病学情况。
2017年9月至10月期间，我们收集了提交至我们实验室进行医护人员健康检查的血清样本，并检测了抗HAV抗体。
总体HAV血清阳性率为5.1%（436份样本中的22份）。与年龄较大的组相比，二十多岁（6.0%）和三十多岁（8.0%）的人群血清阳性率更高。
在这个国际化的时代，对HAV免疫力的下降使医护人员有患该病的风险。作为预防职业感染的一项措施，日本医护人员可能需要接种HAV疫苗。
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