Qiang Zhou, Li-Xin Wan, Qi-Hui You, Jun You, De-Rong Hang, Yi-Xin Huang
Pukou District Center for Disease Control and Prevention, Nanjing City, Jiangsu Province, Nanjing 210031, China.
Key Laboratory of National Health Commission on Parasitic Disease Control and Prevention, Jiangsu Provincial Key Laboratory on Parasite and Vector Control Technology, Jiangsu Institute of Schistosomiasis, China.
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2018 Aug 2;30(4):443-445. doi: 10.16250/j.32.1374.2018110.
To evaluate the molluscicidal effects of various water-free formulations of niclosamide ethanolamine salt against in the field of marshlands along the Yangtze River.
The river beach with snails were selected as the test field in the marshland along the Yangtze River in Pukou District, Nanjing City. A molluscicidal experiment was carried out by the mechanical dusting method with the dustable powder (DP), powder-granule (PG), granule (GR) of niclosamide ethanolamine salt respectively. The snail mortality, corrected mortality, and the reduced rate of snails' density were parallel compared among DP, PG and GR.
On the 3rd day after the dusting, the snail mortality rates were 66.67%, 67.24%, and 66.87% in the DP, PG, and GR groups respectively, on the 7th day after the dusting, the snail mortality rates were 75.36%, 79.73%, and 73.97% in the DP, PG, and GR groups respectively, and there was no significant difference among the groups ( = 0.006, 0.895, both > 0.05). On the 15th day after the dusting, the snail mortality rates were 86.92%, 72.86%, and 71.43% in the DP, PG, and GR groups respectively, and there was a significant difference among the groups ( = 9.709, < 0.01). The snail mortality in the DP group was significantly higher than that in the PG, and GR groups. The curves of the snail corrected mortality and reduced rate of snails'density presented steadily rising trends in the DP group, but presented falling trends in the PG and GR groups on the 15th day after the dusting.
The molluscicidal effect of DP is stable and effective in the marshland along the Yangtze River, but the drift of the powder is still not effectively controlled. It is necessary that the different dosage forms are perfected.
评价氯硝柳胺乙醇胺盐不同无水剂型在长江沿岸沼泽地现场对钉螺的灭螺效果。
选取南京市浦口区长江沿岸沼泽地有钉螺的河滩作为试验现场。分别采用氯硝柳胺乙醇胺盐的可湿性粉剂(DP)、粉粒剂(PG)、颗粒剂(GR),通过机械喷粉法进行灭螺试验。对DP、PG和GR组的钉螺死亡率、校正死亡率及钉螺密度降低率进行平行比较。
喷粉后第3天,DP、PG和GR组的钉螺死亡率分别为66.67%、67.24%和66.87%;喷粉后第7天,DP、PG和GR组的钉螺死亡率分别为75.36%、79.73%和73.97%,各组间差异无统计学意义( = 0.006,0.895,均>0.05)。喷粉后第15天,DP、PG和GR组的钉螺死亡率分别为86.92%、72.86%和71.43%,组间差异有统计学意义( = 9.709,<0.01)。DP组钉螺死亡率显著高于PG组和GR组。DP组钉螺校正死亡率和钉螺密度降低率曲线呈稳步上升趋势,而PG组和GR组在喷粉后第15天呈下降趋势。
DP在长江沿岸沼泽地灭螺效果稳定有效,但粉剂漂移仍未得到有效控制。完善不同剂型很有必要。