Hydroxylapatite cranioplasty directly over dura.

Seven patients who had noticeable defects of their frontal bone were reconstructed with dense hydroxylapatite (HA) particles with or without autogenous bone placed directly over the dura. The results indicate that HA is well tolerated over dura; no meningitis occurred with follow-up of one to 3 1/2 years. The clinical response was excellent and complications were minor, generally related to particle control and settling.