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HGNC采用的官方统一命名法要求使用首字母缩写CCN1 - 6,并分别停止使用CYR61、CTGF、NOV和WISP 1 - 3。

The official unified nomenclature adopted by the HGNC calls for the use of the acronyms, CCN1-6, and discontinuation in the use of CYR61, CTGF, NOV and WISP 1-3 respectively.

作者信息

Perbal Bernard, Tweedie Susan, Bruford Elspeth

机构信息

President International CCN Society, Nice, France.

HUGO Gene Nomenclature Committee, EMBL-EBI, Hinxton, CB10 1SD, UK.

出版信息

J Cell Commun Signal. 2018 Dec;12(4):625-629. doi: 10.1007/s12079-018-0491-1. Epub 2018 Nov 5.

Abstract

An examination of the confusion generated around the use of different acronyms for CCN proteins has been performed by the editors of the HUGO Gene Nomenclature Committee upon the request of the International CCN Society Scientific Committee. After careful consideration of the various arguments, and after polling the community of researchers who have published in the field over the past ten years, the HGNC have decided to adopt and approve the CCN nomenclature for all 6 genes. Effective October 2018, the genes referred to as CYR61, CTGF, NOV and WISP1-3 will be respectively designated by the gene symbols CCN1-6 with corresponding gene names « cellular communication Q2 network factor 1-6 ». We believe that this decision will be a step towards better communication between researchers working in the field, and will set the stage for fruitful collaborative projects. Accordingly, the Journal of Cell Communication and Signaling, the official journal of the International CCN Society, available both in print and online, constitutes a unique window into the CCN field. This official nomenclature will benefit the international scientific community that is supported by the established and renowned professionalism of the Springer-Nature publishing group.

摘要

应国际CCN协会科学委员会的要求,HUGO基因命名委员会的编辑们对围绕CCN蛋白使用不同首字母缩略词所产生的混淆进行了审查。在仔细考虑了各种论点,并对过去十年在该领域发表过文章的研究人员群体进行调查后,HGNC决定采用并批准所有6个基因的CCN命名法。自2018年10月起,分别称为CYR61、CTGF、NOV和WISP1 - 3的基因将分别由基因符号CCN1 - 6指定,并具有相应的基因名称“细胞通讯网络因子1 - 6”。我们相信,这一决定将朝着该领域研究人员之间更好的交流迈出一步,并将为富有成效的合作项目奠定基础。因此,国际CCN协会的官方期刊《细胞通讯与信号转导杂志》既有印刷版也有网络版,构成了进入CCN领域的一个独特窗口。这种官方命名法将使国际科学界受益,该科学界得到了施普林格 - 自然出版集团既定且著名的专业精神的支持。

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