Li Yuanyuan, Yu Fan, Niu Lina, Hu Wei, Long Yong, Tay Franklin R, Chen Jihua
State Key Laboratory of Military Stomatology & National Clinical Research Center for Oral Diseases & Shaanxi Key Laboratory of Oral Diseases, Department of Prosthodontics, School of Stomatology, The Fourth Military Medical University, Xi'an 710032, Shaanxi, China.
Department of Immunology, The Fourth Military Medical University, Xi'an 710032, Shaanxi, China.
J Clin Med. 2018 Nov 6;7(11):417. doi: 10.3390/jcm7110417.
The relationship between bruxism and tooth wear is contentious in the literature. The pathophysiological processes of tooth wear may be complicated by the relationship between bruxism and gastroesophageal reflux disease (GERD). The objective of this study was to evaluate the associations among bruxism, GERD, and tooth wear. Two complementary studies were performed: a case-control study to verify the linkage between GERD and bruxism and a cross-sectional study on the same cohort to establish the connection between GERD and tooth wear in bruxism patients. A cohort of 363 consecutive bruxism patients and 363 matched control participants were recruited. Gastroesophageal reflux disease was diagnosed in accordance with the Montreal criteria. Tooth wear was scored based on the index recommended by Smith and Knight. Logistic regression analyses were performed. After adjustment, GERD was identified as a risk factor of bruxism. Bruxism with reflux symptoms for extensive time-periods was associated with severe tooth wear for the whole dentition (odds ratio, 4.70, 95% confidence interval, 2.04⁻10.83). Increased odds ratios for severe tooth wear were also found in all tooth locations and palatal/lingual and occlusal/incisal surfaces of bruxism patients with GERD for extensive time-periods. In conclusion, strong associations were identified among bruxism, GERD, and tooth wear.
磨牙症与牙齿磨损之间的关系在文献中存在争议。牙齿磨损的病理生理过程可能因磨牙症与胃食管反流病(GERD)之间的关系而变得复杂。本研究的目的是评估磨牙症、GERD和牙齿磨损之间的关联。进行了两项互补性研究:一项病例对照研究以验证GERD与磨牙症之间的联系,以及对同一队列进行横断面研究以确定磨牙症患者中GERD与牙齿磨损之间的联系。招募了363名连续的磨牙症患者和363名匹配的对照参与者。根据蒙特利尔标准诊断胃食管反流病。根据史密斯和奈特推荐的指数对牙齿磨损进行评分。进行了逻辑回归分析。调整后,GERD被确定为磨牙症的一个危险因素。长时间有反流症状的磨牙症与全口牙齿的严重磨损相关(比值比,4.70,95%置信区间,2.