Sand J J, Biller J, Aschenbrener C A
Eur Neurol. 1987;27(3):167-72. doi: 10.1159/000116151.
Nonbacterial thrombotic endocarditis (NBTE) is a presentation of an occult malignancy. The clinical, laboratory and postmortem findings of a 44-year-old man with osteopetrosis and NBTE are reported. A small apical bronchogenic carcinoma was found on postmortem examination. A thorough search for malignancy should be made in patients with unexplained cerebral emboli, especially if hematologic abnormalities are present. There is presently no evidence that anticoagulation or other treatment is beneficial.
非细菌性血栓性心内膜炎(NBTE)是隐匿性恶性肿瘤的一种表现形式。本文报告了一名患有骨质石化症和NBTE的44岁男性的临床、实验室及尸检结果。尸检发现一个小的肺尖支气管源性癌。对于不明原因脑栓塞患者,尤其是存在血液学异常的患者,应进行全面的恶性肿瘤筛查。目前尚无证据表明抗凝或其他治疗有益。