HLA - B27基因座的分子生物学
Molecular biology of the HLA-B27 locus.
作者信息
Weiss E H, Bloemer K, Doerner C, Kuon W, Lang M, Pohla H, Schattenkirchner M, Riethmüller G
出版信息
Br J Rheumatol. 1988;27 Suppl 2:12-8. doi: 10.1093/rheumatology/xxvii.suppl_2.12.
Abstract
The molecular biology of the HLA-B27 locus is reviewed. The HLA-B27 gene itself does not differ between healthy individuals and ankylosing spondylitis patients. Several unique features of the HLA-B27 molecule have been identified and one epitope was proposed to cross-react with bacterial proteins.
摘要
对HLA - B27基因座的分子生物学进行了综述。健康个体和强直性脊柱炎患者之间的HLA - B27基因本身并无差异。已确定了HLA - B27分子的几个独特特征，并提出了一个表位与细菌蛋白发生交叉反应。
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