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使用后采集数字滤波器提高低场 NMR 弛豫测量中的信噪比和分辨率。

Enhancing signal-to-noise ratio and resolution in low-field NMR relaxation measurements using post-acquisition digital filters.

机构信息

Universidade de São Paulo, Instituto de Química de São Carlos, São Carlos, Brazil.

Schlumberger Brazil Technology Integration Center, Rio de Janeiro, Brazil.

出版信息

Magn Reson Chem. 2019 Sep;57(9):616-625. doi: 10.1002/mrc.4806. Epub 2018 Dec 17.

Abstract

The traditional way to enhance signal-to-noise ratio (SNR) of nuclear magnetic resonance (NMR) signals is to increase the number of scans. However, this procedure increases the measuring time that can be prohibitive for some applications. Therefore, we have tested the use of several post-acquisition digital filters to enhance SNR up to one order of magnitude in time domain NMR (TD-NMR) relaxation measurements. The procedures were studied using continuous wave free precession (CWFP-T ) signals, acquired with very low flip angles that contain six times more noise than the Carr-Purcell-Meiboom-Gill (CPMG) signal of the same sample and experimental time. Linear (LI) and logarithmic (LO) data compression, low-pass infinity impulse response (LP), Savitzky-Golay (SG), and wavelet transform (WA) post-acquisition filters enhanced the SNR of the CWFP-T signals by at least six times. The best filters were LO, SG, and WA that have high enhancement in SNR without significant distortions in the ILT relaxation distribution data. Therefore, it was demonstrated that these post-acquisition digital filters could be a useful way to denoise CWFP-T , as well as CPMG noisy signals, and consequently reducing the experimental time. It was also demonstrated that filtered CWFP-T method has the potential to be a rapid and nondestructive method to measure fat content in beef and certainly in other meat samples.

摘要

提高核磁共振(NMR)信号的信噪比(SNR)的传统方法是增加扫描次数。然而,这种方法会增加测量时间,对于某些应用来说可能是不可行的。因此,我们已经测试了使用几种后采集数字滤波器来提高时域 NMR(TD-NMR)弛豫测量中的 SNR,最高可达一个数量级。该程序使用连续波自由进动(CWFP-T)信号进行研究,这些信号采用非常低的翻转角进行采集,比相同样品和实验时间的 Carr-Purcell-Meiboom-Gill(CPMG)信号包含多 6 倍的噪声。线性(LI)和对数(LO)数据压缩、无限脉冲响应低通(LP)、Savitzky-Golay(SG)和小波变换(WA)后采集滤波器将 CWFP-T 信号的 SNR 提高了至少 6 倍。最佳滤波器是 LO、SG 和 WA,它们在 SNR 增强方面具有很高的性能,同时对 ILT 弛豫分布数据没有明显的失真。因此,证明了这些后采集数字滤波器可以有效地去除 CWFP-T 和 CPMG 噪声信号中的噪声,从而减少实验时间。还证明了滤波后的 CWFP-T 方法有可能成为一种快速、无损的测量牛肉(当然还有其他肉类样品)中脂肪含量的方法。

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