Comparative study of the phenolic profile, antioxidant and antimicrobial activities of leaf extracts of five L. (Cupressaceae) taxa growing in Turkey.

The purpose of this study was to conduct a comparative evaluation of some biological properties of methanol and water extracts of leaves of five taxa growing in Turkey: L. var. (), L. var. Pall. (), Labill. (), L. subsp. (), L. subsp. (Sibth. & Sm.) Ball. (). The antioxidant properties were examined ; both in the DPPH and in the reducing power tests, methanol extract resulted the most active (IC = 0.09 ± 0.01mg/mL and ASE/mL = 2.56 ± 0.06). In the TBA assay, methanol extract exhibited the highest activity (IC = 4.39 ± 0.47 μg/mL). The extracts displayed bacteriostatic activity against , and methanol extract resulted the most effective (MIC = 19.53 μg/mL); no effect on the biofilm formation was observed. The extracts resulted non-toxic in the lethality bioassay. Finally, the phenolic profile of the methanol extracts was characterized by HPLC-PDA/ESI-MS.