使用电子von Frey麻醉计和SMALGO对健康猫进行机械阈值测量的评分者间和设备间可靠性
Inter-rater and inter-device reliability of mechanical thresholds measurement with the Electronic von Frey Anaesthesiometer and the SMALGO in healthy cats.
作者信息
Adami Chiara, Lardone Elena, Monticelli Paolo
机构信息
Department of Clinical Sciences and Services, Royal Veterinary College, University of London, London, UK.
Department of Veterinary Science, University of Turin, Turin, Italy.
出版信息
J Feline Med Surg. 2019 Oct;21(10):979-984. doi: 10.1177/1098612X18813426. Epub 2018 Nov 22.
OBJECTIVES
The aim of this study was to compare the Electronic von Frey Anaesthesiometer (EVF) and the Small Animal ALGOmeter (SMALGO), used to measure sensory thresholds in 13 healthy cats at both the stifle and the lumbosacral joint, in terms of inter-rater and inter-device reliability.
METHODS
Two independent observers carried out the sets of measurements in a randomised order, with a 45 min interval between them, in each cat. The inter-rater and inter-device reliability were evaluated by calculating the inter-rater correlation coefficient (ICC) for each pair of measurements. The Bland-Altman method was used as an additional tool to assess the level of agreement between the two algometers.
RESULTS
The mean ± SD sensory thresholds measured with the EVF were 311 ± 116 g and 378 ± 178 g for the stifle and for the lumbosacral junction, respectively, whereas those measured with the SMALGO were 391 ±172 g and 476 ± 172 g. The inter-rater reliability was fair (ICC >0.4) for each pair of measurements except those taken at the level of the stifle with the SMALGO, for which the level of agreement between observers A and B was poor (ICC = 0.01). The inter-device reliability was good (ICC = 0.73; = 0.001). The repetition of the measurements affected reliability, as the thresholds obtained after the 45 min break were consistently lower than those measured during the first part of the trial ( = 0.02).
CONCLUSIONS AND RELEVANCE
The EVF and the SMALGO may be used interchangeably in cats, especially when the area to be tested is the lumbosacral joint. However, when the thresholds are measured at the stifle, the inter-observer reliability is better with the EVF than with the SMALGO. The reliability decreases when the measurements are repeated within a short time interval, suggesting a limited clinical applicability of quantitative sensory testing with both algometers in cats.
目的
本研究旨在比较电子von Frey麻醉计（EVF）和小动物ALGO计（SMALGO）在测量13只健康猫的 stifle关节和腰骶关节感觉阈值方面的评分者间和设备间可靠性。
方法
两名独立观察者对每只猫进行测量，测量顺序随机，每次测量间隔45分钟。通过计算每对测量的评分者间相关系数（ICC）来评估评分者间和设备间的可靠性。采用Bland-Altman方法作为评估两种ALGO计之间一致性水平的附加工具。
结果
用EVF测量的 stifle关节和腰骶关节的平均±标准差感觉阈值分别为311±116 g和378±178 g，而用SMALGO测量的分别为391±172 g和476±172 g。除了用SMALGO在stifle关节水平进行的测量外，每对测量的评分者间可靠性均为中等（ICC>0.4），观察者A和B之间在该水平的一致性较差（ICC = 0.01）。设备间可靠性良好（ICC = 0.73；P = 0.001）。测量的重复影响了可靠性，因为在45分钟休息后获得的阈值始终低于试验第一部分测量的阈值（P = 0.02）。
结论及意义
在猫中，EVF和SMALGO可以互换使用，特别是当测试区域是腰骶关节时。然而，当在stifle关节测量阈值时，EVF的观察者间可靠性优于SMALGO。当在短时间间隔内重复测量时，可靠性会降低，这表明两种ALGO计在猫中进行定量感觉测试的临床适用性有限。
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