2014-2015 年塞拉利昂埃博拉病毒病疫情期间的死产和新生儿死亡监测。
Stillbirths and neonatal deaths surveillance during the 2014-2015 Ebola virus disease outbreak in Sierra Leone.
机构信息
Epidemic Intelligence Service, Centers for Disease Control and Prevention (CDC), Atlanta, GA, USA.
Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, CDC, Atlanta, GA, USA.
出版信息
Int J Gynaecol Obstet. 2019 Feb;144(2):225-231. doi: 10.1002/ijgo.12722. Epub 2018 Dec 19.
OBJECTIVE
To determine the rate of stillbirth and neonatal death reporting and testing for Ebola virus during the 2014-2015 Ebola virus disease (EVD) outbreak in Sierra Leone.
METHODS
A cross-sectional study was performed using information from the Sierra Leone National Ebola Laboratory database to identify stillbirths and neonatal deaths that had been tested for Ebola virus from July 2, 2014, to October 18, 2015. Outcomes included the percentage of all tested deaths attributable to stillbirths and neonatal deaths, the proportion of stillbirths and neonatal deaths attributable to Ebola virus, and the annualized rate of stillbirths and neonatal deaths.
RESULTS
In total, 1726 stillbirths and 4708 neonatal deaths were tested for Ebola virus, representing 2.6% and 7.2% of the total deaths tested (n=65 585), respectively. Of these, 25 stillbirths and neonatal deaths tested positive, accounting for 0.3% of EVD cases. In 2015, the annualized total number of reported stillbirths was higher than expected (3079 vs 1634), whereas reported neonatal deaths were lower (6351 vs 7770).
CONCLUSIONS
Stillbirth and neonatal death reporting and testing improved over time. Systematic recording of these indicators might be used alongside retrospective surveillance to respond to the adverse effects of EVD on maternal and child health and guide response efforts for subsequent outbreaks.
目的
确定 2014-2015 年塞拉利昂埃博拉病毒病（EVD）疫情期间埃博拉病毒死产和新生儿死亡报告和检测率。
方法
使用塞拉利昂国家埃博拉实验室数据库中的信息进行横断面研究，以确定 2014 年 7 月 2 日至 2015 年 10 月 18 日期间接受过埃博拉病毒检测的死产和新生儿死亡病例。结局包括归因于死产和新生儿死亡的所有检测死亡的百分比、归因于埃博拉病毒的死产和新生儿死亡的比例以及死产和新生儿死亡的年化率。
结果
共有 1726 例死产和 4708 例新生儿死亡接受了埃博拉病毒检测，分别占检测死亡总数（n=65585）的 2.6%和 7.2%。其中，25 例死产和新生儿死亡检测呈阳性，占 EVD 病例的 0.3%。2015 年，报告的死产总数高于预期（3079 例 vs 1634 例），而报告的新生儿死亡数则低于预期（6351 例 vs 7770 例）。
结论
死产和新生儿死亡报告和检测工作随着时间的推移而改善。系统记录这些指标可能会与回顾性监测一起使用，以应对 EVD 对母婴健康的不利影响，并指导后续疫情的应对工作。
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