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主动脉骑跨栓塞的诊断与治疗

Diagnosis and Treatment of Aortic Saddle Embolism.

作者信息

Ding Xiangjiu, Liu Yang, Su Qingbo, Hu Sanyuan, Jiang Jianjun

机构信息

Department of Vascular Surgery, Qilu Hospital, Shandong University, Jinan, People's Republic of China.

Department of Vascular Surgery, Qilu Hospital, Shandong University, Jinan, People's Republic of China.

出版信息

Ann Vasc Surg. 2019 Apr;56:124-131. doi: 10.1016/j.avsg.2018.08.094. Epub 2018 Nov 24.

Abstract

BACKGROUND

Acute aortic occlusion is a rare but life-threatening medical condition that can result from aortic saddle embolism, thrombosis of an atherosclerotic aorta, or aortic dissection. Herein are described the diagnostic and therapeutic characteristics for a series of patients with aortic saddle embolism.

METHODS

A retrospective review of medical records was performed for patients receiving treatment for aortic saddle embolism at a university hospital in China between January 2001 and September 2017. Demographic, clinical, ancillary testing, treatment, and outcome data were collected and analyzed.

RESULTS

Eighteen patients (10 women and 8 men) with a mean age of 53.8 years were included. The most commonly associated cardiac diseases were atrial fibrillation or atrial flutter (89%); rheumatic heart disease, valvular heart disease, or both (72%); and congestive heart failure (56%). Rest pain was present in all patients, and sensory or motor deficits were present in 12 patients (67%). Computed tomography (CT) angiography was performed for all patients. Seventeen patients (94%) presented with aortic embolism below the renal arteries. Fifteen patients (83%) underwent bilateral transfemoral embolectomy, and 3 patients (17%) received no intervention. Fasciotomy was performed for 9 patients in 14 limbs. The overall mortality rate was 33%, with a postprocedure mortality rate of 20%. Major morbidity occurred in 60% of patients. Six lower extremities were amputated in 4 patients, and acute renal failure developed in 4 patients. The incidence of postembolectomy internal iliac artery embolism was 58% (11 of 19 iliac arteries), and pelvic ischemia developed in 1 young patient.

CONCLUSIONS

Aortic saddle embolism is uncommon but associated with high morbidity and mortality. CT angiography is recommended for diagnosis, and bilateral transfemoral embolectomy is the preferred treatment. Postembolectomy internal iliac artery embolism was common, and prevention of pelvic ischemia should be considered for young patients.

摘要

背景

急性主动脉闭塞是一种罕见但危及生命的疾病,可由主动脉骑跨栓塞、动脉粥样硬化性主动脉血栓形成或主动脉夹层引起。本文描述了一系列主动脉骑跨栓塞患者的诊断和治疗特点。

方法

对2001年1月至2017年9月在中国一家大学医院接受主动脉骑跨栓塞治疗的患者的病历进行回顾性研究。收集并分析人口统计学、临床、辅助检查、治疗及结局数据。

结果

纳入18例患者(10例女性和8例男性),平均年龄53.8岁。最常见的相关心脏疾病是心房颤动或心房扑动(89%);风湿性心脏病、瓣膜性心脏病或两者兼有(72%);以及充血性心力衰竭(56%)。所有患者均有静息痛,12例患者(67%)出现感觉或运动功能障碍。所有患者均进行了计算机断层扫描(CT)血管造影。17例患者(94%)表现为肾动脉以下的主动脉栓塞。15例患者(83%)接受了双侧股动脉取栓术,3例患者(17%)未接受干预。对14条肢体中的9例患者进行了筋膜切开术。总死亡率为33%,术后死亡率为20%。60%的患者发生了严重并发症。4例患者的6条下肢被截肢,4例患者出现急性肾衰竭。取栓术后髂内动脉栓塞的发生率为58%(19条髂动脉中的11条),1例年轻患者出现盆腔缺血。

结论

主动脉骑跨栓塞并不常见,但发病率和死亡率较高。建议采用CT血管造影进行诊断,双侧股动脉取栓术是首选治疗方法。取栓术后髂内动脉栓塞很常见,对于年轻患者应考虑预防盆腔缺血。

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