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烧伤虚弱指数的制定:一种预测老年烧伤患者预后的指标。

Development of the Burn Frailty Index: A prognostication index for elderly patients sustaining burn injuries.

机构信息

Burn Center, Grady Memorial Hospital, 80 Jesse Hill Jr Dr SE, Atlanta, GA, 30303, USA; Department of Surgery, Emory University Hospital, 1364 Clifton Rd NE, Atlanta, GA, 30322, USA.

Burn Center, Grady Memorial Hospital, 80 Jesse Hill Jr Dr SE, Atlanta, GA, 30303, USA.

出版信息

Am J Surg. 2019 Jul;218(1):87-94. doi: 10.1016/j.amjsurg.2018.11.012. Epub 2018 Nov 14.

Abstract

BACKGROUND

Frailty has demonstrated enhanced prognostic ability for elderly patient morbidity. The aim was to create a burn-specific frailty index for elderly patients and compare it to commonly used scoring systems in burn management.

METHODS

From 2013 to 2017, we prospectively surveyed a randomized cohort of patients ≥65-years-old previously admitted to our burn unit. Prognostic comparisons with 6 commonly used indices and multivariate risk analyses were performed.

RESULTS

Of 100 included patients, n = 32 were classified as frail. The mean patient age was 73.0 ± 6.8-years with a median follow up of 20.9 months. There were 13 moralities in total, 12 occurred in the frail group including 5 in-house mortalities. Patients classified as frail had significantly more complications (p < 0.001), non-home discharges (p < 0.001), ICU admissions, and longer hospital and ICU lengths of stay (p < 0.001), decreased 1 and 3-year survival (p = 0.001). The BFI was identified as an independent predictor of mortality (p = 0.001) and course-altering diagnoses including sepsis/septic shock, ARDS/ALI, and AKI.

CONCLUSIONS

The Burn Frailty Index accurately predicts morbidity and mortality in elderly frail patients suffering burn injuries.

摘要

背景

虚弱已经证明对老年患者发病率具有增强的预后能力。目的是为老年患者创建一个专门的烧伤虚弱指数,并将其与烧伤管理中常用的评分系统进行比较。

方法

我们从 2013 年到 2017 年,前瞻性地调查了我们烧伤病房以前收治的随机队列的≥65 岁的患者。与 6 种常用指数进行预后比较,并进行多变量风险分析。

结果

在 100 名纳入的患者中,n=32 例被归类为虚弱。患者的平均年龄为 73.0±6.8 岁,中位随访时间为 20.9 个月。共有 13 例死亡,其中 12 例发生在虚弱组,包括 5 例院内死亡。被归类为虚弱的患者并发症显著更多(p<0.001),非家庭出院(p<0.001),ICU 入院,以及更长的住院和 ICU 住院时间(p<0.001),1 年和 3 年生存率降低(p=0.001)。BFI 被确定为死亡率的独立预测因子(p=0.001)和改变病程的诊断,包括败血症/感染性休克、ARDS/ALI 和 AKI。

结论

烧伤虚弱指数能准确预测患有烧伤的老年虚弱患者的发病率和死亡率。

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