Khawaja Imran, Spurling Benjamin C., Singh Shantanu
Joan C. Edwards School of Medicine
Marshall University
Rapid eye movement (REM) sleep behavior disorder (RBD) is a REM sleep parasomnia characterized by dream enactment during sleep. Patients often act out their dreams during the REM stage of sleep. Clinical features during sleep include abnormal vocalizations, abnormal motor behavior, and altered dream mentation. This enactment may be violent and can lead to injury to themselves or others without any conscious awareness. A patient can recall the contents of the dream upon awakening. Most patients with REM behavior disorder will eventually manifest neurodegenerative diseases like parkinsonism, dementia with Lewy bodies, or multisystem atrophy. There are also secondary causes of RBD associated with parkinsonism, narcolepsy, or the use of antidepressant medications. A patient may be warned about the future development of these neurological disorders. Treatment consists of preventive measures while sleeping to avoid injury to both the patient and their bed partner. In severe cases, the patient may be prescribed melatonin or clonazepam.
快速眼动(REM)睡眠行为障碍(RBD)是一种以睡眠中出现梦境演绎为特征的快速眼动睡眠异态睡眠。患者常在快速眼动睡眠阶段将梦境付诸行动。睡眠期间的临床特征包括异常发声、异常运动行为和梦境思维改变。这种演绎可能很暴力,并且会在患者没有任何意识的情况下导致自身或他人受伤。患者醒来后能够回忆起梦境内容。大多数快速眼动睡眠行为障碍患者最终会出现神经退行性疾病,如帕金森综合征、路易体痴呆或多系统萎缩。也有与帕金森综合征、发作性睡病或使用抗抑郁药物相关的快速眼动睡眠行为障碍的继发原因。可以向患者警示这些神经系统疾病的未来发展情况。治疗包括睡眠时的预防措施,以避免患者及其同床伴侣受伤。在严重的情况下,可能会给患者开褪黑素或氯硝西泮。