黑色素瘤患者区域淋巴结的当前管理
Current management of regional lymph nodes in patients with melanoma.
作者信息
Bartlett Edmund K
机构信息
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY.
出版信息
J Surg Oncol. 2019 Jan;119(2):200-207. doi: 10.1002/jso.25316. Epub 2018 Nov 27.
Abstract
The publication of recent randomized trials has prompted a significant shift in both our understanding and the management of patients with melanoma. Here, the current management of the regional lymph nodes in patients with melanoma is discussed. This review focuses on selection for sentinel lymph node biopsy, management of the positive sentinel node, management of the clinically positive node, and the controversy over the therapeutic value of early nodal intervention.
摘要
近期随机试验的发表促使我们对黑色素瘤患者的理解和管理发生了重大转变。在此，将讨论黑色素瘤患者区域淋巴结的当前管理方法。本综述重点关注前哨淋巴结活检的选择、前哨淋巴结阳性的管理、临床阳性淋巴结的管理以及早期淋巴结干预治疗价值的争议。
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本文引用的文献
1
Melanoma Staging: American Joint Committee on Cancer (AJCC) 8th Edition and Beyond.
Ann Surg Oncol. 2018 Aug;25(8):2105-2110. doi: 10.1245/s10434-018-6513-7. Epub 2018 May 30.
2
Lymph node blood vessels provide exit routes for metastatic tumor cell dissemination in mice.
Science. 2018 Mar 23;359(6382):1408-1411. doi: 10.1126/science.aal3662.
3
Lymph node metastases can invade local blood vessels, exit the node, and colonize distant organs in mice.
Science. 2018 Mar 23;359(6382):1403-1407. doi: 10.1126/science.aal3622. Epub 2018 Mar 22.
4
Stratifying SLN incidence in intermediate thickness melanoma patients.
Am J Surg. 2018 Apr;215(4):699-706. doi: 10.1016/j.amjsurg.2017.12.009. Epub 2017 Dec 14.
5
Transected thin melanoma: Implications for sentinel lymph node staging.
J Surg Oncol. 2018 Mar;117(4):567-571. doi: 10.1002/jso.24930. Epub 2017 Nov 30.
6
Adjuvant Nivolumab versus Ipilimumab in Resected Stage III or IV Melanoma.
N Engl J Med. 2017 Nov 9;377(19):1824-1835. doi: 10.1056/NEJMoa1709030. Epub 2017 Sep 10.
7
Adjuvant Dabrafenib plus Trametinib in Stage III BRAF-Mutated Melanoma.
N Engl J Med. 2017 Nov 9;377(19):1813-1823. doi: 10.1056/NEJMoa1708539. Epub 2017 Sep 10.
8
Melanoma Sentinel-Node Metastasis.
N Engl J Med. 2017 Aug 31;377(9):892. doi: 10.1056/NEJMc1708918.
9
Predictors of false negative sentinel lymph node biopsy in trunk and extremity melanoma.
J Surg Oncol. 2017 Dec;116(7):848-855. doi: 10.1002/jso.24743. Epub 2017 Jun 26.
10
Completion Dissection or Observation for Sentinel-Node Metastasis in Melanoma.
N Engl J Med. 2017 Jun 8;376(23):2211-2222. doi: 10.1056/NEJMoa1613210.
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